Multicentric Investigation And Evaluation Of Long-term Health-related Quality Of Life For Severe Extensive Burn Patients

Backgrounds:Despite considerable/significant advancements in burn survival rate with thedevelopment of medicine, the patients, during rehabilitation period, are undertakingserious physical and psychological burdens including disfigurement/the change ofappearance, the loss of function（of the limbs）, pain and other burn complications. Andvarious complex factors like these led to the decrease of health-related quality of life（HRQoL）. Lately, a growing number of countries begins to show solicitude for theHRQoL of the severe extensive burn patients, and has carried out numerous relatedresearch.Objective:To find out the current quality of life of the extensive burn population in Chinapreliminarily, and clarify the the main factors which affect the patients’ HRQoLaccording to the related predictors, and provide a reference for formulating the clinicaltreatment guidelines of severely extensive burn patients and the the long-termrehabilitation strategy of the survival ones.Methods:1. Patient selectionAccording to the inclusion criteria,80extensive burn patients（≥50%TBSA）were enrolled from1999to2011. They were treated in Changhai hospital in Shanghai,the7th people’s hospital of Shanghai, the1st people’s hospital of Zhengzhou and the2nd hospital affiliated to Kunming Medicine college.2. The professionals will get the patients’ basic information,and fulfill the casereport form.Under the professionals’help,the patients have to complete the threequestionnaires such as Short Form-36Medical Outcomes Survey (SF-36), Brief Versionof Burn Specific Health Scale (BSHS-B) and Michigan Hand Outcome Questionnaire（MHQ）.At last there is an attached information questionnaire need to be finished.3. Statistical Methods According to the scores of the questionnaires,we’ll give a statistical description to thedata with the methods of Shapiro-Wilk test,homogeneity of variance test,Student-ttest,Wilcoxon rank test,chi-square test, to evaluation the Long-term HRQoL of thesevere extensive burn patients.In combination with clinical practice and literaturedata,we make a Pearson correlation analysis or Spearman rank correlation analysis,withthe predictors and the physical component summary and the mental componentsummary.We hope to select out the closely related ones to make a multivariate linearanalysis to find more information.Results:We selected80patients in group.Their average age is36.50±19.00.（the age whenthey were burned） The patients’ average burned surface area is72.50±29.50%TBSA.The SF-36tells us that, in the domains of physical functioning, rolelimitations due to physical problems, pain, social functioning and role limitations due toemotional problems compared with population norms,the patients scored significantlylower than the standard population.The multivariate linear analysis tells us that,the III°burned area,the length of the time between the research and the injury and wether theaccepted a skin-grafting on their hands or not are related with the PCS.It also tellsthat,the times of the plastic surgery,the length of the time between the research and theinjury and the marriage condition are related with the MCS.The BSHS-B shows thelowest scores in domains of heat sensitivity,work and body image.The MHO shows noideal results except the domain of activity of daily living.Conclusions:Generally speaking, the Long-term HRQoL of the severe extensive burn patients islow.Their general conditions and basic functions are acceptable.When thepatients’functions that they relay on to live were lose,added with the changes of theirlooks,they get many psychological burdens in their minds.Thankfully,the research tellsthat,the mental and physical problems has a tendency to improve as time flies.