Related Factors Of Type2Diabetes With Lower Limb Arterial Lesions

Objectives: To retrospectively analyze the clinical features and related factors of patientswith type2diabetes lower limb artery pathological changes.Methods: Collecting the data of patients with type2diabetes lower limb arterypathological changesfrom Jiangsu province people’s hospital endocrinology and vascularsurgery clinical during2011-2013. According to whether the lower limb arterial occlusionwas divided into blocking and non-blocking gro-up,using t test and chi-square test to comparetwo groups of patients with clinical characteristics,apply Logistic regression and ROCcurve to analyze the related factors influencing the lower limb arterial occlusion.Results: After compared of age[(70.00±9.32) years VS(60.81±9.73)years], course ofthe disease[(13.09±8.15)yearsVS(9.85±7.15)years], blood uric acid[(363.26±103.87)VS(314.45±91.43) μ mol/l], blood urea nitrogen[(7.67±1.94) mmol/lVS(6.29±2.02)mmol/l], serum creatinine[(82.85±20.04) μ mol/lVS(71.54±23.77) μ mol/l], urinaryAlbumin to Creatinine Ratio and coronary heart disease[(151.27±219.61)mg/mmolVS(64.07±135.68）mg/mmol]，cerebral(36.1%VS1.61%)，infarction(27.8%VS6.45%),Hypertensive(83.3%VS56.45%),Diabetic Peripheral Neuropathy (Diabetic Peripheral Neuropathy,DPN)(47.2%VS12.9%,), Diabetic Nephropathy(Diabetic Nephropathy, DN)(83.3%VS22.6%),occlusion group patients’ had a significantly higher incidencethannon-blocking group.(p <0.05)；Multiple Logistic regression analysis revealed that the blood uricacid level and incidence of coronary heart disease and cerebral infarction with lower limbarterial occlusion was significantly positive correlation (p<0.05)；ROC curve analysis showed that the blood uric acid level is higher than380μmol/l,65.38%of patients with type2diabeteslower limb artery occlusion merger.Conclusions: Patients type2diabetes occlusive cardiocerebrovascular events occurredmore often in patients who have a lower extremity artery pathological changes, blood uric acidlevels in patients with type2diabetes is the independent risk factors of lower limb arteryocclusion.