Study On The Relative Factors Of Breast Cancer Of Upper Limb Lymphedema After Formation

Objective:To study the risk of breast cancer-related lymphedema.Analysis early breast conserving surgery patients undergoing more than three years of upper extremity lymphedema side with age, body mass index, whether the advantages of arms, with or without hypertension, presence or absence of upper limb functional training, injury, infection of the relationship,which can provide reference information for the prevention of breast conserving surgery upper extremity lymphedema, in order to improve early breast conserving surgery in patients with long-term survival of the quality of life.Methods:A retrospective analysis was made on clinical data of145cases, which were stage I breast cancer confirmed by operation and had chemotherapy or rchemotherapy after breast conservative surgery, from august2008to september2010.Count lymphedema of affected limbs and the risk factors for breast cancer-related lymphedema:age, BMI, dominant hand, hypertension, postoperative functional exercise, infection.The clinical data were analyzed retrospectively to analysis of reasons of the risk factors for breast cancer-related lymphedema.Results:Incidence of breast cancer-related lymphedema in this results is34.48%(50/145)。Relationship between observation indexes and breast cancer-related lymphedema:Incidence of surgery-related lymphedema was positively correlated with old age, increaseed BMI, hypertension, infection, and postoperative functional exercise, which has statistical significance (P<0.05or P<0.01). While dominant hand was meaningless to surgery-related lymphedema.Multiple regression analyses were performed on the results:Screening out3factors associated with breast cancer after breast conserving surgery for upper extremity lymphedema in alpha=0.05level,which were infection (OR=8.565), postoperative functional exercise (OR=-7.120), hypertension (OR=1.869). In the analysis of Logistic regression, odds ratio (OR) can be used as relative risk (RR) approximation. The influence of3factors on lymphedema were ifection, postoperative functional exercise, hypertension, in which postoperative functional exercise is a protective factor. Conclusion:Limb lymphedema after breast conserving surgery for early breast cancer is Closely related to the formation and the individual patient factors which mainly were ifection,postoperative functional exercise,hypertension.Besides keeping weight and blood pressure within the normal range, avoiding the affected limb off pressure and weight loading, the patients would have postoperative functional exercise and avoid infection to prevent and mitigate lymphedema.Postoperative follow-up should also focus on the question of the quality of life of patients with breast cancer recurrence, as Guide the patients to reasonably upper limb functional exercise, avoid any infectious lesions,treat theinfection actively,to Improve long-term survival quality.