The Comparison Of Mid To Long-term Follow-up Between Surgical Ventricle Restoration And Non-surgical Treatment For Left Ventricular Aneurysm

ObjectiveThis study evaluate the effects of surgical treatment by comparing early and long-term left ventricular size and function, survival rates, MACCEs and recurrence rates of heart failure with non-surgical treatment.Methodswe assembled 117 patients who received surgical treatments of left ventricular aneurysm during 1997-2014 in our cardiovascular surgery department as surgical group, meanwhile we matched 117 patients as non-surgical group by 1:1 rate from 413 patients who received non-surgical treatment only during 1997-2014 in our hospital with 12 preoperative variables (age, gender, BMI, infarction interval, infarction location, smoke, preoperative complications, heart function classification, LVESVI, EF, MI level, number of diseased vessels). We followed up left ventricular functional including heart function classification, left ventricular diameter, wall thickness, left ventricular end-systolic volume and end-systolic volume index, left ventricular end-diastolic volume and end-diastolic volume index, ejection fraction, survival rate, MACCEs and recurrence rate of heart failure statistically and comparatively.Results1. Left ventricular diameter, left end-systolic volume and left end-systolic volume index, left end-diastolic volume and left end-diastolic volume index decreased after the surgical ventricular restoration operation compared with non-surgical group, which was statistically significant (P<0.05). The NYHA classification and left ventricular ejection fraction was improved after the operation compared with non-surgical group, which was statistically significant (P<0.05). The result confirmed that the operation of left ventricular restoration not only reshaped the ventricular but also improve cardiac function.2. The survival rates after the operation were better than the non-surgical group and the differences were statistically significant (P<0.05).3. The MACCEs and recurrence rate of heart failure after the operation were lower than the non-surgical group and the differences were statistically significant (P<0.05).ConclusionThe surgical ventricular restoration is a safe and effective operation compared with non-surgical treatment for the patients with left ventricular aneurysm, which improves heart function, survival rates and qualities of life.