| Objective:Explore the risk factors of endometrial cancer in Harbin, and provide the basis for clear screening appropriate crowd; explore the distribution of TCM syndromes in patients with endometrial cancer, to find out the regularity of things, for the further prospective clinical study, implementation of individualized treatment, the development of the basic principles of treatment, develop basic prescription reference.Methods:The June 2013-December 2014 Heilongjiang Provincial Tumor Hospital of Gynecology treated by surgery, clinical data integrity, and endometrial cancer patients with histologically confirmed a total of 178 cases as a patient group statistics. Take the same area of residence, age difference of not more than 5 years, excluding uterine fibroids and other malignancies healthy women as a control group, a total of 174 cases of statistics. TCM Syndrome Distribution analysis of endometrial cancer, and improve their follow-up data, the establishment of the clinical follow-up data database, using univariate and multivariate logistic regression analysis of risk factors for endometrial cancer.Results:1. Patients with endometrial cancer were aged from 70 to 30 years, and the average age was 52.64+4.72 years. The peak age was 50-60 years old, accounting for 56.7% of all cases.The younger than 40 years of age accounted for 9.5%, and the proportion of postmenopausal and postmenopausal patients was 31% and 69%, and the younger patients were younger.. The urban and rural patients were 51.4%28.4%,the proportion of the urban patients was higher than that of the rural areas. Degree of culture in early high school, primary school, junior college and above degree accounted for 55%,29% and 16%; means of payment of medical cost is mainly medical insurance for urban workers and the new rural cooperative medical insurance,52.7% and 23.0%; occupational status of workers, peasants and self-employed accounted for 69.1%,17.3% and 11.2%; marital status married, unmarried or divorced/widowed were 78.4% and 21.6%.2. The clinical symptoms with irregular vaginal bleeding patients 138 cases, lower abdominal pain or package piece of 26 cases, vaginal discharge in 6 cases, lower abdominal bulge in 4 cases, irregular menstruation, leucorrhea abnormal in 4 cases. (14.6%,3.3%,2.2%,2.2%, 77.5%).3.There were 122 cases of Department of internal medicine complication,68.5% of all cases,42 cases of obesity,50 cases of hypertension and diabetes mellitus..4.This study in endometrioid adenocarcinoma of 147 cases,14 cases of mixed type carcinoma, other types of cancer, a total of 17 cases (including clear cell carcinoma in 5 cases,3 cases of papillary adenocarcinoma, undifferentiated carcinoma (1 case), squamous cell carcinoma in 8 cases), respectively, of the total of investigation number 82%, 7.8% and 9.5%. There were 96 cases of endometrial carcinoma, I stage, phase â…¡, stage â…¢, IV stage,51 cases,23 cases,8 cases (54%,13%,4%, 29%).5. The single factor analysis showed that endometrial cancer occurrence and more factors, the BMI is greater than or equal to 25 kg/m2, early menarche, infertility, obesity, hypertension, diabetes, hormones replacement therapy, he tamoxifen and endometrial cancer family history, these factors for the high risk factors of endometrial cancer.6. In the study of TCM syndrome type of higher incidence is due to downward flow of damp heat type, incidence for 17 81 people, secondly is poisoning caused by damp stasis junction 48 people, ganyuxuerexing 24 people, kidney yin deficiency, spleen deficiency type 8, respectively, of the total number of surveys of 45.5%,26.9%,13.4%,9.6% and 4.5%, and endometrial cancer basic disease machine line. Damp heat type and damp and blood stasis type as the main card type, consider the evil of damp heat and the incidence of endometrial carcinoma is closely related to, treatment can be used Qingrejiedu dampness medicine on immune Fuzheng based.Conclusion:1.The incidence of endometrial cancer in Harbin city and surrounding areas are younger, constitute higher than the suburban city patients.2.BMI is greater than or equal to 25 kg/m2, early menarche, infertility, obesity, hypertension, diabetes, hormones replacement therapy, he used tamoxifen and endometrial cancer family history, these factors for the high risk factors of endometrial carcinoma. Recommended for high-risk groups to take the appropriate measures to prevent the active treatment of the original disease, to carry out regular physical examination, the establishment of a disease crisis awareness.3. Perimenopausal patients, especially in patients with late age of menopause, menstrual cycle disorders arise if, irregular vaginal bleeding, increased by the amount of other clinical manifestations, patients at higher risk of endometrial cancer, should be vigilant.4.For patients with endometrial cancer for TCM syndrome classification study can initially-revealed the clinical features of endometrial cancer syndromes, should be added with heat and dampness antidote in righting the basic immunization. |
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