The Analysis Of Changsha Urban District Occupation Population Metabolic Syndrome Prevalence In Different Gender And Its Related Risk Factors

AimsMetabolic syndrome is a common chronic disease, metabolic aggregation of pathological state including lipid metabolism, impaired glucose tolerance, central obesity and high blood pressure, the genetic and environmental factors lead to it. In recent years, the incidence is increasing. the main risk factors including age, race, family history, smoking, drinking, diet structure was irrational, lack of physical activity habits. those risk factors were worked together to increased promotion of target- organ damage that eventually leads to the heart, brain, kidney and vascular diseases, seriously affects the life quality of patients, besides, the disease caused a huge economic burden. Early intervention can interrupt or slow down to the progression of the disease.The factors of sexuality about metabolic syndrome incidence reports are still in controversial. In order to investigate the metabolic syndrome prevalence of different sexuality, to study the meaning of prevention and treatment to the metabolic syndrome with different gender, this study used questionnaire survey to collect lifestyle among participants who took routine annual physical examinations living habits of employers and retired workers in the physical examination center of Hunan Province People’s Hospital. According to the results of physical examinations. the ms prevalence survey and analysis of related factors by gender had been carry out. Compared with different gender MS prevalence of abnormal metabolism and the differences in each group, the aim was for the clinical screening of high- risk population, and provide scientific reference for reasonable selection of intervention measures.MethodsFrom July, 2014 to September, 2014, the questionnaire survey of living habits such as smoking, drinking, the sleeping time, the exercise time, salt intake, fat intake and pressure level, the past duration and familiy history of hypertension, coronary heart disease and diabetes. of diabetes, has been used(for those people who have been taken the hospital physical examinations), and collect the examination data, such as body mass index, systolic blood pressure, diastolic blood pressure, fasting plasma glucose, triglyceride, high density lipoprotein cholesterol, total Cholesterol 、 low density lipoprotein Cholesterol.There were 2365 participants(according to 1296 males and 1069 females) met the requirement.according to the sexuality, those participants would be affix to different groups, ages were considered for classification. Each groups’ waist circumference, body mass index, fasting plasma glucose, triglyceride, high density lipoprotein cholesterol, total Cholesterol、low density lipoprotein Cholesterolsystolic blood pressure, diastolic blood pressure, triglyceride, high density lipoprotein were presented by the standard deviation(X + S). By using analysis of variance, t test, and X2 test to compare differences among groups and subgroups. By using the non- conditional Logistic regression analysis, the related risk factors of hypertension and metabolic syndrome have been comprehended, P<0.05 had got statistical significance.Results1.In the survey, there were 333 metabolic syndrome patients, the prevalence rate was 14.08%, 224 patients were male, the prevalence rate of male was 17.28%, 109 patients were female, the prevalence rate of female was 10.20%, the prevalence rate of male was higher than female(P < 0.01).2.In the survey, the detection abnormal rate was hypertension(44.01%), the high level of waist- height- ratio(43.47%), hypertriglyceridemia(30.37%), the abnormal mtabolism of overweight/obesity(29.81%), the high level of waist circumferene(23.51%), the high level of total Cholesterol(15.18%), the low level of high density lipoprotein cholesterol(13.53%), the high level of low density lipoprotein cholesterol(13.07%), the high level of fasting blood glucose or diabetes(9.56%). The abnormal rate of male was higher than female(P < 0.01).3.According to the various metabolic components of MS abnormal number classification, male and female without component were 21.84% and 51.13%, patients who got one abnormal indicator were 25.54% and 30.48%, patients who got two abnormal indicators were 30.40% and 11.13%, patients who got three abnormal indicators were 6.27% and 9.49%, patients who got four abnormal indicators were 5.94% and 3.27%, patients who got five abnormal indicators were 1.85% and 0.65%; obviously, the abnormal rate of male were higher than female.4.Patients with abnormal metabolism, the rate of males were much higher than that of females.With one abnormal indicator, the hypertension was biggest,(62.28% versus 53.11%); with two abnormal indicators, male patients with hypertension and hypertriglyceridemia(32.23%), female patients with hypertension and the high level of waist circumferene,(32.77%); with three abnormal indicators, the hypertension, and the high level of waist circumferene and high hypertriglyceridemia were very common, for males were 35.77% and for females were 32.83%.5.Devided the groups by age, male in age less than 35 years old, 35 ~ 44 years old, 45 ~ 54 years old, 55 ~ 64 years old and over 65 years old different subgroups of metabolic syndrome were detected in 4.09%, 17.02%, 24.91%, 26.42% and 20.79%, while the female were 2.41%, 4.42%, 11.20%, 20.93% and 20.71%. The prevalence rate of male has positive correlation with age before 65 years, the prevalence in 55 ~ 64 yeas reached the highest value, after 65 years the prevalence rate decreased; and the prevalence rate of female has positive correlation with age. Age were less than 65 years old, the male’s prevalence rate of metabolic syndrome was higher than female’s(P < 0.01), when passed 65 years of age, the prevalence of metabolic syndrome had no significant difference(P > 0.05).6.In the Logistic regression analysis, age, body mass index, family history of diabetes and heavy pressure have positive correlations with morbidity of metabolic syndrome.For females, high- sugar diet also have the positive correlations with morbidity of metabolic syndrome.For males, smoking, high- sodium and high- fat diet have positive correlations with morbidity of metabolic syndrome, and the exercise time was have the opposite effectConclusions1.In the survey, the prevalence rate of metabolic syndrome was14.08%, male had much higher prevalence than that of females(17.28% versus 10.20%),and the prevalence rate was consistent with the prevalence rate of 2014 in China.2.Use the components of metabolic syndrome as the standard of metabolic abnormality, the most common metabolic abnormalities was hypertension, the second was hypertriglyceridemia, the third was the high level of waist circumferene, the fourth was the low level of high- density lipoprotein cholesterol and the last was the high level of fasting blood glucose or diabetes.3.In the logistic regression analysis, the main risk factors of female’s metabolic syndrome were age, body mass index, family history of diabetes, heavy pressure and high- sugar diet.4.In the logistic regression analysis, the main risk factors of male’s metabolic syndrome were age, body mass index, family history of diabetes, heavy pressure, smoking, high- sodium and high- fat diet, the exercise time was the protective factors of metabolic syndrome.