The Clinical Effect Observation About Kunduan Tianqi Scorpions Soup On Treating In The Mid-to-late Ankylosing Spondylitis

Object:To observate the clinical efficacy and safety of Kunduan Tianqi Scorpions soup on Treating in the mid-to-late ankylosing spondylitisMethods:Collection of outpatient and inpatient department of the in the mid-to-late AS patients eligible for a total of 60 cases,who were oraled Kunduan Tianqi Scorpions soup((tripterygium hypoglaucum hutch 30g, Panax notoginseng 3g, Scorpions 8g, Dipsacus asperoides 15g)). Water decoction method:first using 500ml water cook the Kunming Begonia, pseudo ginseng, scorpion, a total of 3.5 hours to cook, then cook wihe Radix dipsaci for 0.5 hours, add up to 4 hours decoction, decoction of 150ml points 3 times after meals, during Three months we should appraise and note clinical effectiveness and safety Around the 4、8 and 12 week。Observation index:the patient’s age, sex, The course of the disease, Flame indices score (ESR and CRP), Bath Ankylosing Spondylitis Functional Index, Bath Ankylosing Spondylitis Disease Activity Index, Joint axis pain VAS score, patient global evaluation of VAS score, ASAS20, ASAS50, ASAS70 the compliance rate before treatment at 4 weeks,8 weeks,12 weeks. Monitoring of blood, index of liver, kidney index before treatment at 4 weeks,8 weeks,12 weeks after every survey time.Adverse record.Evaluation Criteria:Evaluation using international ankylosing spondylitis evaluation team recommended standard ASAS20,50,70 reaction scheme for ankylosing spondylitis.Results:In treatment for 4 weeks,8 weeks,12 weeks, The Kunduan Tianqi Scorpions group soup could effectively improve the patient’s clinical symptoms and signs, and reduced inflammatory laboratory index (ESR, CRP) role. At the end of the 8 week course of treatment in patients with general self evaluation scores of VAS, BASFI, BASDAI, VAS, ESR, spinal pain score CRP, ASAS20/50 rate reflects the degree of improvement were better, had the advantages of quick, strong, and with the extension of time, its clinical effect was more obvious. The treatment process of Kunduan Tianqi Scorpions soup in the mid-to-late ankylosing spondylitis, could better control the disease, prevent further deterioration, delaying irreversible joint damage. The main adverse reactions and toxic side effects of Kunduan Tianqi Scorpions soup Decoction were the skin and blood system damage, reproductive toxicity, this study showed no adverse events occurred, and to the relevant treatment can relieve symptoms.To sum up, Kunduan Tianqi Scorpions soup Only four herbs, side effect was relatively small, and the prescription streamlined, in improving the clinical curative effect of the patients and reduced the patient’s medical costs, save medical resources, so to achieve good clinical efficacy but also get better effect of health economics. Adverse reactions, the prescription for no fertility requirements of patients in the mid-to-late stage or in postmenopausal women with definite curative effect, but for patients with fertility requirements, need to obtain the consent of patients can be used.Conclusion:First:Kunduan Tianqi Scorpions soup could alleviate the patients in the mid-to-late stage of low back pain, stiffness and other symptoms, with rapid onset of action is strong, and with the extension of time, its clinical effect was more obvious.Second:Kunduan Tianqi Scorpions soup could play a very good reduce inflammation index, play anti-inflammatory analgesic effect.Third:ASAS20/50/70 rate in the short term, the success rate of ASAS20/50 were better, and the success rate of ASAS70 for longer time to observe its curative effect.Four.The main adverse reactions and side effects were reproductive toxicity and blood system, skin damage, no obvious adverse events occurred.Five:Kunduan Tianqi Scorpions soup Decoction rigorous, simple recipe, exact therapeutic effect in the mid-to-late ankylosing spondylitis, and the cost was relatively low...