Meta-Analysis Of The Long-term Clinical Viewing Of The Effectiveness After The Revascularization Of Chronic Total Occlusion

Objective: To assess the long-term clinical effectiveness after revascularization of coronary arteries with chronic total occlusion by Meta-analysis.Methods: Comprehensive collection of randomly compared study of CTO patients’ revascularization through computer retrieval of data bases such as PubMed、EMBASE、CBM、 CNKI、VIP、wan fang Date Cochrane, and subsidiary retrieval by means of back tracking method etc. Arranging for two appraisers to independently screening literature, select material/papers, evaluate quality and have cross-check in the light of selected and exclusion standard, and then use Stata/SE11.0 statistic software provided by Cochrane to conduct Meta-analysis.Results: 19 papers at home and abroad have been considered up to standard and finally picked out, covering 3146 patients with CTO. The evaluation result of Meta-analysis shows. 12 months after the treatment of the CTO patients by PCI, the incidence of MACE has been remarkably reduced [RR=3.74,95%CI(3.32-4.21),P=0.000]; LVEF clearly increased [RR=10.34, 95%CI(10.31-10.36), P=0.000]; 6 walking test obviously improved [RR=5.82, 95%CCI(4.97-6.66),P=0.000]; ECG QTd evidently shortened [RR=-0.57,95%CI(-0.62-0.51), P=0.971]，making QTd<50ms, so showing marked statistic significance compared with the condition before the treatment by PCI.Conclusions: Vascular reconstruction can markedly reduce the incidence of the patients’ MACE and target-vessel revascularization (TVR), can improve the patients’ cardiac function, their standard of living and exercise endurance. Better long-term prognosis can be expected. It can stabilize the patents’ electro-physiological function, prevent malignant arrhythmia and prolong the patient’s life.