The Correlation Study Of Spleen Deficiency On Osteoporosis

Intention:Through questionnaires,doing bone density examination and other factors related spleen,such as muscle strengh and muscle content in clinical cases; using the statistical software, analysis the relationship between these factors and bone mineral density,so as to discuss the effect of spleen deficiency on the occurrence of osteoporosis,spleen defficiency is the promoting factors of osteoporosis in a certain extent.Method:This study was a crosssectional study,using the questionnaire survey method.In 3 months of collecting 400 cases in outpatient and ward (excluding body metal, serious illness, unconsciousness, action inconvenience, not long standing and over 90years old and incomplete data)from Feburary,2014 to March,2015 in Xiyuan Hospital,carries on the questionnaire survey; using Dual energy X-ray bone density instrument to exam bone mineral density,measured by bioelectrical impedance method(BIA) in human muscle, fat, moisture and so on; test muscle strength, grip strength,strength of lower limbs (including test number 30s up),3M turn back time,6m walking time andwalking pace etc.. According to the symptoms and tongue and pulse of patients, divided intonon spleen deficiency group and spleen deficiency group, analysis the data between bone density and muscle factors, and find their correlation.Result:1.The correlation coefficient between grip strength, muscle content,30s number,6m speed up and the lumbar spine,femurbone mineral density is a positive correlation between them;the correlation coefficient between 6m walking the femoral and lumbar bone mineral density is a negative correlation betweenthe two; the correlation coefficient between 3m turn back time and total hip BMD isa negative correlation between the two.2.Bone mineral density is positively related to fat, body weight, height, BMI in femur and lumbar spine; there is no relationship between the water、each part of the limb muscles index andfemur and lumbarvertebrae bone mineral density.3.Muscle grip,and muscle contant in spleen deficiency group are lower than those in non spleen deficiency group, p<0.01, the difference is statistically significant;the bone mineral density of total hip bone mineral density and lumbar vertebrae L3in spleen deficiency group in were lower than that in non spleen deficiency group, p<0.01, the difference was statistically significant.4.Stratification of muscle content and grip strength, BMI.Bone density in small grip group is lower than that in strength grip group,bone density in less content of muscle group is lower than that in large musclecontent group,p=0.000<0.01,the difference was statistically significant;the lumbar spine and femur bone density in Body mass index (BMI) small group is lower than that inhigh group, p=0.000<0.01, the difference is statistically significant.5.The total incidence rate of fracture in non spleen deficiency group is 23.9%, in spleen deficiency group is 30.1%, the difference between the two goup has no statistically significance after the chi square test,but in numerical,spleen deficiency group in the total fracture occurrence rate is higher than that in non spleen deficiency group;after gender stratification, spleen deficiency group of women in the fracture incidence is 89.23%, female in non spleen deficiency group is 70.45%,the difference between two groups has statistically significance after the chi square test.6.The correlation coefficient between grip strength, muscle content and 30s set up is a positively correlated between them; the correlation coefficient between grip strength and 3m turn back and 6mwalking time isa negative correlation between them; the correlation coefficient between muscle contentand 6mwalking timeis negatively correlation between the two; the correlation coefficient between 30s set up,3m turn back and 6m walking time is negative correlation between them; the correlation coefficient between 3m turn back and 6m walking time ispositive correlation between them.Conclusion:Spleen governing muscles of limbs, spleen deficiencydecreased muscle strength, muscle content.Gastrointestinal absorption of spleen deficiency, bone lack of nutrition, which led to the occurrence and development of osteoporosis.The grip strength and muscle content are positively correlated to the bone in this study, so that the spleen deficiency is positively correlated to the bone, it is a important factor in bone massdecrease, bone density in small grip group is lower than that in strength grip group, bone density in less content of muscle group is lower than that in large muscle content group,the difference was statistically significant,and then it can be verified that spleen deficiency can affect the development of osteoporosis, and it can promote the development of spleen deficiency in some extent;in the case of fracture incidence, the incidence of female fracture in the spleen deficiency group was higher than that of the non spleen deficiency, and the correlation between spleen deficiency and the occurrence of female fracture was related.Fat, weight, height, BMI are positively correlated to the bone density. Especially when BMI> 23kg/m2, the higher BMI is, the higher the bone mineral density is. Although BMI for other disease is a risk factor, but for osteoporosis is a protective factor, so even if old people do not have enough muscle content for bone density more some of the fat is the benefits of a certain.