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Investigation Of Migraine-related Dietary Factors And The Effects Of Diet Control In Migraineurs

Posted on:2016-09-19Degree:MasterType:Thesis
Country:ChinaCandidate:Y B ZhangFull Text:PDF
GTID:2284330461489137Subject:Clinical medicine
Abstract/Summary:PDF Full Text Request
Objective Migraine is a group of recurrent headache disorders. It’s the most common primary headache in neurology clinic. Migraine interferes with the normal work and life of patients severely, and it also brings some of the financial burden. The etiology and pathogenesis of migraine are still not clear, but there are many patients with acute exacerbation of incentives among which the role of dietary factors are very prominent. Therefore, migraine sufferers should develop a reasonable diet. This will be an effective way to prevent migraine attacks. In this research, for migrainuers, the dietary factors related epidemiological survey and evaluation the effectiveness of therapeutic measures would be discussed.Methods Seventy patients with migraine,30 patients with tension-type headache were selected randomly from June 2014 to December 2014 in headache specialized clinic of Shandong Provincial Hospital. The general information and detailed medical history of all subjects and the level of headache severity were collected. Visual analogue scale was used. All patients underwent questionnaires during headache intermittent. Data analysis was done with SPSS 21.0 software package. The measurement data was analyzed with chi-square test or Mann-Whitney testf the count data among different groups was analyzed with t test or Mann-Whitney test. The difference was considered statistically significant when P<0.05.Results1. The incidence of diet related factors in migraine group was 42.9% (30/70). It was obviously higher than that of the tension-type headache group 10.0% (3/30). There was a significant statistical difference (P<0.05).2. The incidence of irregular eating in migraine group was 31.4%(22/70); in tension-type headache group, the proportion was 10.0% (3/30). The difference was statistically significant (P<0.05). In male patients the irregular eating incidence was 30.4%(7/23), while in female patients it was 30.2%(15/47), the difference was not statistically significant (P>0.05). Fifteen patients with MA,55 patients with MO.7 patients with MA have irregular eating habit,15 patients with MO have irregular eating habit. The incidences of irregular eating habit of two types migraine showed no statistical difference (P>0.05).Patients with irregular eating have more episodes (P<0.05), and the average duration of a single onset and ache degree showed no statistical difference (P>0.05).3.Twelve (17.1%) cases in migraine group have food-triggers, while 0 cases in TTH group. The difference was statistically significant (P<0.05).Six patients with MA have food triggers,6 patients with MO have food triggers. The incidences of food triggers of two types migraine showed statistical difference (P<0.05). Patients with MA are more likely to have food triggers than patients with MO.4. In the 12 cases with food-triggers in migraine group, there were 7 females (0.15%), and 5 males (0.22%), the difference was not statistically significant (P>0.05). The reported foods include:alcohol, coffee, chocolate, salt, bananas, fat, soy sauce, cakes, corn (one patient has two kinds of food-triggers, while another patient has four). The proportion of each kind of reported food were as follows: wine 8.5% (6/71), coffee 2.8% (2/71), chocolate 2.8% (2/71), salt 1.4%, bananas 1.4%, fat 1.4%, soy sauce 1.4%, cakes 1.4%, corn 1.4%. In male patients the major reported food was wine, and in female patients include coffee, chocolate, bananas, fat, soy sauce, cakes, corn.Food-induced migraine has more episodes and severer ache extent than non-food induced migraine (P<0.05), but the duration of each kind showed no difference (P>0.05).5. According to the diagnostic and curative effect criteria of migraine, patients with dietary factors sufferer from light, medium and severe headache are 0 cases,6 cases,24 cases respectively before receiving treatment. And patients without dietary factors sufferer from light, medium and severe headache are 2 cases,19 cases,19 cases respectively before receiving treatment. There are significant differences between these two groups (P>0.05).6. There are no significant differences in frequency, duration and severe degree between patients with food-related factors and patients without food-related factors after receiving foundational treatment and diet control (P>0.05). Patients with dietary factors sufferer from light, medium and severe headache are 24 cases,6 cases,0 cases respectively after receiving treatment. And patients without dietary factors sufferer from light, medium and severe headache are 29 cases,10 cases,1 case respectively after receiving treatment. There is no significant difference between these two groups (.P>0.05).7.Seventy migrainuers include EM 43 cases and CM 27 cases. There is no significant difference between these two groups in eating habits, food triggers, anorexia. Chi-square test is made with P>0.05. The incidence of diet related factors in EM patients has no difference with CM patients, or diet related factors have no effect on transformation from EM to CM.Conclusions1. The incidence of irregular eating and food trigger in migrainuers are significantly higher than that of the tension-type headache patients, but there is no difference between different genders in migraine group. Patients with MA are more likely to have food triggers than patients with MO.2. Irregular eating can cause more episodes of migraine, but has no relationship with the duration or severity. Patients with inducing-foods have more frequently episodes and severer aching extent. But the duration shows no difference. However, diet-related factors have no relationship with transformation from EM to CM.3. Male and female have different categories in inducing foods. Male patients usually have attack after drinking wine, while female patients have a broader spectrum. But in general, patients with diet related factors suffer severe headache than those without.4. Treatment effects in patients with diet related factors through drug therapy and diet control can be very satisfied. Clinical practitioner should pay attention to diet-related factors carefully and give diet control to them.
Keywords/Search Tags:Migraine, Tension-type headache, Eating habits, Food-induced factors, Diet control
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