Clinical Characteristics And Efficiency Of Interventional Therapy Of Coronary Artery Involvement In Takayasu’s Arteritis

[Objective] To analyze the clinical characteristics, efficiency of interventional therapy of coronary artery involvement in Takayasu’s arteritis.[Methods] We retrospectively studied the patients who had more than 50% diameter reduction of coronary artery by angiography, of 98 consecutive hospitalized patients with Takayasu’s arteritis from 2000 to 2013 in PUMC hospital.[Results] There were totally 6 cases with coronary artery involvement of Takayasu’s arteritis, which accounted for 6.1%(6/98) of all the hospitalized patients with Takayasu’s arteritis. All the cases were female, aged 15-51 (32 ±16) years. All the cases presented with typical angina pectoris, with depression of ST segment in electrocardiogram. Of the 6 cases, the myocardial enzyme elevated in 5 cases, fulfilled the diagnosis of non-ST elevated myocardial infarction.4 cases had peripheral arterial involvement, while the other 2 cases had only coronary involvement. Coronary angiography was useful for definitive diagnosis. Coronary ostia were most frequently involved.5 patients received successful coronary revascularization with drug-eluting stent, which improved the symptom of angina pectoris. However,1 patient developed restenosis in the stent 3 months after PCI.[Conclusions] Coronary artery involvement in Takayasu’s arteritis is not rare, usually the ostia. The patient usually present with non-ST elevated myocardial infarction. PCI with drug-eluting stent can improve the symptom, but the long-term effect should be investigated further.