Analysis Of The Risk Factors Of Radical Operation In Eldly Colorectal Cancer Patients

Background and Objective In recent years, colorectal cancer incidence has increased, and with the aging of the world’s population growing, the proportion of elderly patients with colorectal cancer is increasing. Currently, radical surgery is the most effective treatment for the treatment of colorectal cancer. However, as the function of physiological body organs of elderly patients have declined, tolerance for surgery have significantly reduced, often accomplied with a variety of underlying diseases, and the risks of surgical complications also increased.This study aims to exploring risk factors of elderly patients’ colorectal cancer surgeries, in order to intervene the risk factors related and improve, increase the rate of colorectal cancer radical operation, and improve the overall prognosis of patients by analyzing the clinical data of patients with colorectal cancer regression analysis about 238 patients older than 70.Methods This paper retrospectively analyzed 238 cases of colorectal cancer clinical surgeries about intraoperative and postoperative complications collected by The Third Affiliated Hospital of Anhui Medical University(The First People’s Hospital and The Lakeside Hospital of Hefei, Anhui Province) Gastrointestinal Surgery between January 2008 to December 2012.SPSS 12.0 statistical analysis software was used for analyzing the statistical result row. Using the posibility whether postoperative complications in patients with colorectal cancer as the dependent variable and the various clinical factors as independent variables for single factor regression analysis. Meanwhile, using the posibility postoperative complications whether colorectal cancer patients as the dependent variable for multivariate analysis.Results 1. Preoperative complications: in 238 cases of patients, preoperative total of 158 cases of underlying diseases(66.4%), including 56 cases of diabetes(23.5%), with cardiovascular diseases such as hypertension, coronary heart disease, and arrhythmia are 81 patients(34.0%), with respiratory diseases such as chronic bronchitis, bronchial asthma and so on are 41 cases(17.2%), combined with other diseases are 11 cases(4.6%). There are 67 cases with two or more diseases(28.2%).2. Surgical complications and postoperative complications are 99 cases(41.6%), including 40 cases of respiratory complications: pulmonary infection are 33 cases, bronchial asthma are 4 cases, acute respiratory failure are 3 cases; cardiovascular complications are 14 cases; Rapid tachyarrhythmias or frequent contractions are 7 cases, 5 cases of heart failure, myocardial infarction are 2 cases; 12 cases of anastomotic leakage; we uesd Dixon radical anastomotic fistula for 5 cases, the line of colon resection anastomosis fistula for 7 cases; there are 19 cases with wound infection, wound dehiscence are 2 cases, postoperative gastrointestinal bleeding are 3 cases, urinary tract infection are 5 cases, two cases of deep vein thrombosis, surgical side injury(ureter) are 2 cases. there are 3 cases of deathdue to postoperative pulmonary infection, and respiratory and circulatory failure, two cases of death due to myocardial infarction, the mortality rate is 2.1%.3. The single factor analysis of relevant factors surgical complications: The results show that the difference among four factors that the merger basic diseases, hypoalbuminemia, operation time, of multi-visceral resection was statistically significant(P < 0.05).4. Surgical complications related factors of multiple factors analysis: The results showed that the relevant factors: age ≥76 years old, BMI ≥ 23kg/m2, underlying diseases, preoperative anemia, hypoalbuminemia, operation time ≥200min and combined with organ resection are the risk facts of elderly colorectal cancer patients’ postoperative complications.Conclusion Age ≥ 76 years old, BMI ≥ 23kg/m2, combined with basic diseases, preoperative anemia, hypoalbuminemia, operation time ≥200min, and combined multi-visceral resection were the risk factors of patients with colorectal cancer radical surgery. For elderly colorectal cancer, surgery should be based multidisciplinary individualized comprehensive treatment model. Paying great attaches to the age and overweight factors of colorectal cancer patients, strengthening management of the basic diseases, anemia and hypoalbuminemia before operation, and selecting high qualification surgery doctor, can reduce postoperative patients with recent complications, make the elderly patients with colorectal cancer radical surgery safe and feasible, and can effectively improve the overall prognosis.