Argon Plasma Coagulation Combined With Cryotherapy On Ulcer Type(and/or Granulomatous) Study On The Efficacy Of Tracheobronchial Tuberculosis

Objective: This paper mainly studies argon plasma coagulation combined frozen type of ulcer the curative effect of tracheobronchial tuberculosis treatment. Argon plasma coagulation(argon plasma coagulation, APC) is also called the argon knife, in recent years gradually used in clinical practice, argon plasma coagulation technology is high frequency current to the electrode of the ionization of argon plasma contactless guide to the treatment group, by heating dry tissue contracture of solidification and the deactivation, ultimately achieve the goal of focal coagulation and hemostasis. This method can effectively treat ulcer type airway TB, relieve patients. Cryotherapy cryotherapy is a damage method of treatment effect of the diseased tissue. Can use of low temperature(70 ℃) of liquid carbon dioxide as refrigerant, the freezing probe placed in the diseased tissue freezing, can make the diseased tissue within the crystal water into ice, destroy cell protein and enzyme system, micro thrombus formation, make the cell stops dividing, excluded patients.The above two methods of treatment of airway TB are effective, and the operation is simple and quick, but combining the two methods, used to treat ulcer type what will be the effect of tuberculosis, and used with pure argon plasma coagulation and to compare whether cryotherapy have more advantages, is rare at home and abroad, this research report. And domestic hospital of argon knife in this field in recent years, freezing treatment did a lot of research, the technology is mature, but its focus is mainly used for treatment of tumor, tuberculous tracheal or bronchial few research. In this paper, we design the argon knife, frozen open to tracheobronchial tuberculosis treatment, controlled clinical research, to observe its efficacy and safety.This article by cryotherapy combine with the argon plasma coagulation method of ulcer type(and/or granuloma type) airway TB test, and adopts grouping test, respectively: argon plasma coagulation group, argon plasma coagulation combined refrigeration, freezing treatment group, treatment group of patients, this paper compares and analyzes the effect of exploration of argon plasma coagulation combined refrigeration of ulcer type(and/or granuloma type) the curative effect of airway TB, update the progress to treating ulcer type airway TB.Methods: Between January 2012 and June 2014, a total of 120 patients with tracheobronchial tuberculosis hospital make a diagnosis and give treatment, the pathology and/or cytology in the diagnosis of tracheobronchial tuberculosis patients, airway stenosis degree of unlimited.Inclusion criteria:(1) The ages 18 to 70 years;(2) The ulcer type(and/or granuloma type) type central airway TB;(3) > 30% choked degree should first remove granulation(frozen/snare/APC);(4) Expected lifetime more than 3 months;(5)Treatments airway did not receive any local treatment within 1 month;(6)To understand the situation of this study and have signed informed with books.First, using the random number table method, 120 cases of patients can be divided into 3 groups: group A and group B, group C, with 40 cases in each group. Among them, the group A with INH 100 mg of submucosal injection + APC; Group B with INH 100 mg of submucosal injection + APC + frozen; Group C by INH 100 mg submucosal injection + freezing. Second, tracking records of each group of patients with clinical manifestations and treatment effects, including: cough, cough up phlegm, wheezing, wheezing sound, etc. Third, key records for 6 months after treatment the curative effect of three groups of patients and the clinical symptoms improved.Results: To compare the effect will be 3 groups, the difference was statistically significant(P < 0.05); Which group B is better than that of group A and group C, the difference was statistically significant(P < 0.05). Three groups before treatment cough, sputum, breathing, symptoms of wheezing sound comparison, there were no statistically significant difference(P > 0.05). Three groups after treatment cough, sputum, breathing, symptoms of wheezing sound comparison, the difference was statistically significant(P < 0.05).才 Which group B is better than that of group A and group C, the difference was statistically significant(P < 0.05).Conclusions: Through this experiment can make us a better understanding of argon plasma coagulation combined frozen treatment the clinical symptoms of ulcer type airway TB, recognize the argon plasma coagulation combined frozen treat ulcer tracheobronchial tuberculosis clinical effect is remarkable, is conducive to better and faster ulcer type airway TB treatment, the treatment is worthy of popularization and application.