Clinical Analysis Of Repeat Transurethral Resection Of Bladder Tumor For Non-muscle Invasive Bladder Tumor

ObjectiveTo explore and investigate the effect of re-TURBT(repeat transurethral resection of bladder tumor) on the prognosis of NMIBC and the indications of re-TUR by comparing the clinical efficiency of TURBT(transurethral resection of bladder tumor) with re-TURBT on non-muscle invasive bladder cancer(NMIBC). MethodsTo review the clinical records as well as follow-up data of 76 patients, who underwent an conventional TURBT and first diagnosed with NMIBC(Ta、T1) from March of 2009 to March of 2013, 31 of them accept a re-TURBT 2-6weeks after the first TURBT, this is the research group, and the 45 patients did not accept re-TURBT are the control group. All cases were treated with routine bladder perfusion chemotherapy(THP)and followed by regular cystoscopy after the initial TUR. 73 cases were follow up for 2 years, 3 cases in the research group were rejected for changing another operation to cure. Observe the rate of residual tumor after the initial TURBT and the difference of pathologic staging between the initial TURBT and re-TURBT in research group. Compare the rates of recurrence and progress of the tumors in two groups. Results:Through comparison of age, gender, number and size of tumor,as well as pathological results(pathology stage and grade) in two groups, we can find out there is no significant difference between two groups(p>0.05). With the pathological results of the re-TUR, we find out 3 cases(10.7%)have the residual tumors after initial TUR. 6 cases of them have an underestimated pathological results after initial TUR. Of the 6 cases, 3 patients first diagnosed with stage Ta(22.2%)were actually in stage T1, 3 case(which were removed from the research group for choosing another therapy)were diagnosed with stage T2,while first diagnosed with stage T1. During the follow-up of 2 years, the recurrence rates of the research group and control group respectively are 21.4% and 55.5%, while the progress rates of the them respectively are 14.2% and 40%. They all have significant difference(p<0.05). The research group could be separated into residue group and non-residue group. By compare of the recurrence and progress rates of the two groups, we can find significant difference(p<0.05)in them. ConclusionsRepeat TURBT could remove the residual tumor of the initial TURBT, decrease the rates of recurrence and progress of non-muscle invasive bladder tumor,acquire an accurate pathology result and guide the next therapy. Patients with high stage tumors(T1),high grade tumors(G3),multiple tumors, larger tumors(>3cm) could benefit better effect from re-TURBT...