Incidence And Risk Factors For Early Postoperative Cognitive Dysfunction In Hui And Han Elderly Patients

Objective：To compare with the incidence for postoperative cognitive dysfunction in Huiand Han elderly ethnic groups, and investigate the risk factors for early POCD in the twoethnic groups.Methods：The300patients were divided into Hui ethnic and Han ethnic group, AmericanSociety of Anesthesiologists (ASA) physical status I to III, aged over60years scheduled forselective surgery under anesthesia. Cognitive assessment was performed by the Mini MentalState Examination (MMSE)1day preoperatively and1day or3to7days postoperatively.300patients were retrospectively analyzed, which were divided into non-POCD group andPOCD group. To compare the incidence of early POCD between the Hui and Han nationality.Age, level of education, preoperative MMSE score, preoperative complications and otherfactors including the length and type of anesthesia, postoperative complications and treatmentin the intensive care unit (ICU) were recorded.Results:107of300elderly patients were diagnosed POCD, the incidence was35.7%.POCD was found in63/148(42.6%) Hui ethnic group compared with44/152(28.9%)Hanethnic group. Logistic regression analysis revealed that the diabetes (OR=5.282),hypertension (OR=4.130), hyperlipemia (OR=3.419) and postoperative respiratorycomplications were the independent risk factors of the early POCD in the Hui elderly patientsand the advanced age (OR=2.711), the illiteracy (OR=3.799), the diabetes (OR=11.808), thehypertension (OR=2.497)were the independent predictors of early POCD in Han elderlypatients(P <0.05).Conclusion:The incidence of early POCD in the Hui ethnic group was significantly higherthan that in the Han ethnic group. The independent predictors for early POCD in the Hui ethnic elderly patients were the diabetes, hypertension, hyperlipemia and postoperativerespiratory complications, the independent predictors for early POCD in Han ethnic elderlypatients were advanced age, illiteracy, diabetes, and hypertension.