Study On Dosimetry Optimization In Chest Wall And Regional Lymph Nodes’s Radiotherapy After Breast Cancer Operation

In our country, postoperative radiation therapy as an effective adjuvant therapy forbreast cancer has made considerable progress, especially in breast-conservingpost-surgery related to precise radiotherapy research has achieved outstanding resultsand widely used in clinical. At the same time, modified radical mastectomy and radicalmastectomy with radiotherapy still occupies a large proportion, and it stays inconventional mode and three-dimensional conformal treatment phase.The aim of thisresearch is to explore the reasons of restricting its radiotherapy technology developmentand facing difficulties, analysis different irradiation technology dosimetrycharacteristics in the planning target coverage and organs at risk, and then comparativeresearch to find the best treatment options.Research through interviews and combined with related reports, analyzes andsummarizes depth reason that constraints modified radical mastectomy precisionradiotherapy applications and research in the current, and according to breast conservingpost-surgery radiotherapy related accurate targeting and dose distribution researchresults, determine the whole research design and research direction. Followed by furtherlist and contrasts four3D-CRT technology in the target volume coverage and organs atrisk by of dosimetry characteristics, and based thereon design and optimization ofintensity modulated radiation field angle, and intensive studied multi-segmentedtangents and the multi-segmented lead door fixed IMRT’s dosimetry distributioncharacteristics. To used to SPSS17statistical software for Varian eclipse TPS patient’splan data within and among groups paired test, and the risk of ipsilateral lung V20changes related factor analysis.The results indicated that multi-segmented lead door fixed IMRT technology notonly to meet the target dose coverage of the clinical requirements, reducing the criticalorgan dose limits, for example ipsilateral lung V20, V30and Dmean, the heart andcoronary left side descending branch arteries’ the average dose etc, and effective controlof the low-dose radiation volume to increase and make it clinically acceptable range.In short, the modified radical mastectomy and radical mastectomy radiotherapy forbreast cancer urgent need for more precise treatment techniques in order to ensure the target dose coverage and organs at risk dose reduce. Mutli-segmented lead door fixedIMRT is probably the most effective way of way, but to ensure its accuracy in clinicalstudies have yet to be implemented further in depth.