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Correlation Analysis Of Ultrasound And Pathology Of Thyroid Nodules

Posted on:2015-03-07Degree:MasterType:Thesis
Country:ChinaCandidate:J LiFull Text:PDF
GTID:2284330434954112Subject:Clinical Medicine
Abstract/Summary:PDF Full Text Request
PurposeColor Doppler ultrasound observation of benign and malignant thyroid nodules image features, combined with the pathological diagnosis of benign and malignant thyroid nodules explore ultrasonography and pathological relationships and relevance, and to improve ultrasound diagnosis of malignant thyroid nodules compliance rate.MethodSelect110cases (125) thyroid nodules do research object, all patients underwent ultrasonography and color Doppler ultrasound examination, and are confirmed by pathology diagnosis. Of which33cases (39nodules) and malignant nodules, select the same period77cases (86nodules) benign nodules. By observing the two-dimensional ultrasound images and Doppler ultrasound features125thyroid nodules presented, statistics ultrasound image diagnosis of malignant thyroid nodules sensitivity and specificity, comparing the ultrasound image benign and malignant thyroid nodules meaning; comparative analysis of these33cases (39nodules) and malignant nodules HE biopsy provides pathological basis.ResultMalignant nodules and thyroid nodules multiple or single no significant relationship. Malignant thyroid nodules dimensional ultrasound image shows:solid nodules (100%), fuzzy boundaries (76.90%), irregular (59.00%), peripheral halo-free (92.30%), echo inequality (94.90%), hypoechoic (94.90%), internal see microcalcifications (69.20%), cervical lymphadenopathy (41.00%); Doppler ultrasound showed internal flow signals based (74.40%). Each ultrasound image diagnosis of benign and malignant thyroid nodules are suggestive of statistical significance (P<0.05). Malignant thyroid nodule biopsy Show:gray cut surface, hard texture; low magnification display more irregular shape (22/39), and more blurred boundaries (30/39), fibrous pseudocapsule (10/39); grit the number of multi-body≥5个HP (26/39), organized by the cancer cells within the lesion (divided into two kinds of follicular and papillary) and fibrous stroma components. Different lesions, the proportion of cells are also different; fibrous stroma have varying degrees of hyaline; between cancer cells and fibrous zonal arrangement or staggered. Conclusion1ultrasound examination of the thyroid nodule detection rate. Two-dimensional ultrasound and color Doppler ultrasound Performance help determine the nature of thyroid nodules.2manifestations of thyroid nodules:irregular, fuzzy boundaries, internal hypoechoic lesions associated with microcalcifications, abnormal sonographic cervical lymphadenopathy and increases the likelihood of malignant lesions.3malignant nodules thyroid ultrasonography and color Doppler characteristics closely associated with pathological types.
Keywords/Search Tags:Thyroid nodules, malignant thyroid nodules, Color Dopplerultrasound, pathology, Peak Systolic Velocity, EndDiastolic Velocity, Resistance Index
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