| Objective:To evaluate values of18F-FDG PET/CT SUVmax in the differential diagnosis of pulmonary lesions, and to look for the best diagnostic boundary value and to discuss the influences of lesion size, and to determine the effects of pathological type on SUVmax. Methods:134patients undergoing18F-FDG PET/CT imaging, after injection of18F-FDG,50minPET/CT images were collected. The imaging results were analyzed using semi-quantitative analysis and they were compared with the follow-up treatment results and pathology results. The ROC curves analysis was used to evaluate differential diagnostic effectiveness of SUVmax to benign and malignant lung lesions. The scatter diagram and the covariance analysis were taken as the statistical methods, the size of the lesions and the effects of pathological type on SUVmax were also studied. Results:SUVmax in lung malignant lesions group was higher than that in benign lesions group (t=6.327,P<0.05), the best cutoff point was4.16for SUVmax on ROC curves, SUVmax>4.16was taken as the diagnosis of benign and malignant threshold, the sensitivity and speciality were0.88and0.82respectively. The scatter diagram was used to analyze the effect of lesion size on SUVmax, the results showed that there was significant association between the lesions SUVmax and the lesion size(r=0.510,P<0.05); Based on the effects of the pathological type such as adenocarcinoma, squamous carcinoma, tuberculosis on SUVmax, the covariance analysis was used to adjust the effects of size, SUVmax in squamous cell carcinomas was greater than the tuberculosis group and the difference was statistically significant (P<0.05). There was no statistically significant difference between the other groups (P>0.05). Conclusion:18F-FDG PET/CT SUVmax had great clinical application value in the differential diagnosis of benign and malignant lung lesions, SUVmax diagnosis value was influenced by many factors. In clinical work,SUVmax alone its haslimitations. |
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