The Efficiency Study On The Treatment Of Promoting Gas And Invigorate The Circulation Of Blood Against Crohn’s Disease Of Gas And Blood Blocking

Objective:To investigate the study of Chinese qi and blood circulation method combined with Western medicine treatment efficacy and colonoscopy performance stagnation type of Crohn’s disease, a clear Integrative therapy therapeutic value for clinical blood stasis type of Crohn’s disease, and analyze the major molecular mechanisms to provide more theoretical and clinical basis for future Integrative therapy of Crohn’s disease.Methods:In line gasification stagnation, blood stasis cubic basis, qi and blood circulation method selected for the rule is, clinical disease subtraction, select diagnosed30patients with Crohn’s disease, TCM is Qi stagnation type, were randomly divided into two groups, namely Chinese medicine combined with western medicine group and the western medicine group,15patients in each group were compared between before and after treatment, the value of Chinese and Western medicine in the treatment of Crohn’s disease in a systematic studyResults:(1) clinical symptoms:After treatment, both groups of patients with abdominal pain, diarrhea and other symptoms significantly improved compared with before treatment, including clinical remission after western medicine group was significantly greater than the simple and efficient Western group, probably because the study sample smaller amounts, it is no statistically significant difference between the two groups (p>0.05).(2) inflammatory activity indicators:Western group therapy after three months, six months, respectively, compared with the previous treatment, the inflammatory activity indicators were significantly decreased (eg CDAI, CRP, ESR, TNF-a), and the difference between groups there was statistically significant (p<0.05), illustrate two different drugs in patients after clinical treatment of inflammatory activity indicators three months, compared with those before treatment significantly decreased after6months; after treatment comparison, in were compared, and Western groups of inflammatory activity index drops three and six months was significantly higher than pure medicine, and the differences between the two groups was statistically significant (p<0.05), and Western groups in reducing reaction described Crohn’s disease on the severity of inflammatory markers was significantly better than western medicine.(3) condition improved indicators: treatment for three months, six months later, after the two groups were compared, all kinds of Chinese and Western group got better indicators (eg HGB, HCT, ALB) increased significantly compared with only western group, and between the two groups the difference was statistically significant (p<0.05), described on the Western group therapy improves disease indicators increased response was better than western medicine group. Microscope (4) repair intestinal inflammation and pathological changes:six months later colonoscopy, compared with mucosal healing and Western group was significantly higher than western medicine group between the two groups, but the difference between his group was not statistically significant (p>0.05).Conclusions:After preliminary studies, integrative medicine therapy in reducing the severity of Crohn’s disease response and indicators activities (such as CDAI, CRP, ESR, TNF-a, etc.) and indicators increased response of Crohn’s disease condition improved (eg HGB, HCT, ALB etc.), etc., its efficacy was significantly better than western medicine, and no significant adverse reactions. However, because this study is not long, and low incidence of Crohn’s disease, leading to the small sample size, so in terms of clinical remission rate and efficient repair and endoscopic mucosal inflammation and pathological changes, with its group There was no significant difference between, it is suggested that investigators later full use of modern science and technology, such as molecular biology techniques, and collect more samples to observe safety indicators (such as WBC, GR%, ALT, AST, etc.), efficacy indicators (clinical improvement, CDAI, ESR, CRP, TNF-a, etc.), her condition improved indicators (eg HGB, HCT, ALB, etc.) as well as endoscopic mucosal inflammation under repair and pathological changes of circumstances. I believe in the expansion of the sample size studies, there will be differences between the two groups was statistically significant, Integrative therapy for Crohn’s disease to provide more effective theoretical and clinical basis. Western clinical use of combination therapy of Crohn’s disease when, in generating the clinical efficacy of the drug did not increase the adverse effects of patients, indicating that the treatment is basically safe.