Clinical Observation Of Xuezhongxiao Of Vasospasm Embolization Granule On Prevention And Treatment Of Aneurysmal Subarachnoid Hemorrhage

Objective: Observed before and after treament in patients with embolization vasospasmincidence of aneurysmal subarachnoid hemorrhage, embolism after bilateral middlecerebral artery blood flow velocity before and after discharge, Glasgow outcome scorechanges, validate the curative effect of eliminating haematoma particles, and toexplore the mechanism of treatment of vascular spasm, and provide scientific basis forthe particles in clinical application.Methods: A total of60patients with aSAH after operation patients, randomly dividedinto teratment group and control group30cases each in30cases; two groups inWestern Medicine Department of internal medicine+neural interventional therapy,the control group with Nimodipine Injection; the treatment group in the control groupbased on the particle dissipation (with hematoma application of TCM formula granuleShenzhen three nine pharmaceutical Limited by Share Ltdproduction) of oral or nasalfeeding; the two groups were14days for a course of treatment, by transcranialDoppler (TCD) examination to determine cerebral vasospasm in patients of the twogroups before and after treatment, the prognosis of Glasgow score for dischargedpatients and3months after, and carries on the analysis statistical comparison. The twogroups before and after treatment of cerebral vasospasm, bilateral middle cerebralartery blood flow velocity, Glasgow outcome score changes.Results：①Compared to the incidence of two groups of patients with cerebralvasospasm: treatment of cerebral vasospasm group, the incidence rate of33%, higherthan70%in control group, by X2test, P <0.05, the difference was statisticallysignificant.②Comparison of two groups of patients of TCD blood flow parameters:seventh days after bleeding,treatment group was126.30±31.31cm/s, independentsamples t test,compared with the control group, the difference was statisticallysignificant (P <0.05).③Comparison of the two groups of patients with Glasgow scores,the independent samples t test, the treatment groupcompared with the control group,the discharge P <0.05, the difference was statistically significant. Conclusion: Xuezhongxiao particles having Huayu Xiezhuo, heat clearing anddetoxifying effect, can effectively prevent embolization of cerebral vasospasm afteraneurysmal subarachnoid hemorrhage cerebral blood flow, promote recovery,improving living ability, clinical curative effect.