Analysis Of Relevant Factors Of Spontaneous Preterm Birth And Its Pregnancy Outcome

Preterm birth refers to the gestation from28weeks to37weeks (196～258)delivery.Preterm delivery according to the reasons can be divided into spontaneouspreterm birth (SPB), Preterm prematurely ruptured membranes (PPROM) andIatrogenic preterm delivery (IPD).SPB is one of the most common types. It is theresult of many factors, like a history of premature birth, low degree of culture, noregularly prenatal, intrauterine infection.etc.Foreign studies have shown thatintrauterine infection can explain about40%of the preterm births occur, therefore,the proportion of different high risk factors of preterm births there may be differences.Gestational age is the main factor which influences the prognosis of premature birth.It has been pointed out that preterm birth at32weeks before has one of the mostcommon complications is neonatal respiratory distress syndrome (NRDS), and itsincidence and mortality were significantly higher than32weeks after. So seeking theclinical characteristics of different gestational ages in SPB is very important to guideclinical prevention works. Because of the chorioamnionitis plays an important role inthe pathogenesis of SPB and PPROM,before both were known as idiopathicpremature birth. Recently, premature rupture of membranes have been pointed outthat it is more likely to cause intrauterine infection, which results to the neonatalasphyxia, neonatal infections, etc.So separating the SPB and PPROM to research thedifferent outcomes of premature infant has a certain clinical value. ObjectiveTo analysis the different composition ratio of delivery high risks in spontaneouspremature birth, explore the pregnancy outcome in different gestational ages anddiscuss whether there is a difference between spontaneous preterm birth and Pretermprematurely ruptured membranes(PPROM) about the Premature infant outcome.MethodsThe clinical features of200singletons patients with spontaneous prematurebirth(SPB) from January2012to December2013was chosen, which was divided intothree groups according the gestational age.The preterm birth group which from28to31+6weeks was designed for group A, the group which from32to33+6weeks wasdesigned for group B,while the group which from34to36+6weeks was designed forgroup C.In the same period patients with preterm premature rupture of membranes(PPROM)in200cases was selected also.ResultsFirstly. The main dangerous factors of200patients with spontaneous pretermbirth is the history of preterm birth or recurrent abortion,followed by the genital TractInfection,the history of threatened abortion in the pregnancy period,etc.Secondly.Inearly preterm birth group of Patients has a high rate of neonatal asphyxia andintracranial hemorrhage,while the moderate preterm group and the light pretermgroup do not have any significant differences in them.Thirdly.The spontaneouspreterm birth patients compared with preterm prematurely ruptured membranes haveno difference in neonatal birth weight, neonatal asphyxia,neonatal intracranialhemorrhage,etc. The neonatal infection rate of SPB is lower than PPROM,while theneonatal pulmonary hyaline membrane disease incidence rate is higher. Thedifference has a statistical significance. ConclusionsFirstly. One of the most common risk factors for spontaneous preterm birth isthe history of recurrent miscarriage.Secondly.The Spontaneous preterm birth before32weeks has a high rate of neonatal asphyxia and neonatal intracranialhemorrhage.Thirdly.There is no significant difference of neonatal asphyxia betweenSpontaneous preterm birth and preterm premature rupture of membranes,while SPBhas a high rate of neonatal pulmonary hyaline membrane disease.