| Objective:Observation of Guiling pa’an Wan for Parkinson disease (Defici ency ofkidn ey and blood stasis type).effect of T C M syndr ome in patients with integral table,UPDRS3.0rating scale, SF-36health questionnaire,Clinical therapeutic effect andsafety of preliminary evaluation of Guiling pa’an Wan.And provide a theoret ical basis.for the development of new drugs and clinical application.Methods: Selected met the inclusion criteria of Parkinson disease (kidney deficiencyand blood stasis type)60cases, according to the control table of random number with1:1ratio divided into treatment group and control group, two groups for30cases.Thecontrol group was given Madopar tablet treatmentand the treatment group in the abovetreatment based on the use of Guiling pa’an Wan treatment.The two groups wereobserved for12weeks.The control group was given Madapar tablte treatmentes. thetreatment group. in the above treatment based on the use of Guiling pa’an Wantreatment.Results:1.1.The TCM syndrome: treatment group total effectiveness96.7%, thecomparison group total effectiveness is83.3%, there was significant difference (P<0.05),description of Guiling pa’an Wan plus Benserazide tablet in the treatment ofParkinson’s disease.(Deficiency of kidney and blood stasis type). efficacy was betterthan western medicine group;2. The two groups after treatment of the TCM syndromes,UPDRS3.0rating scale scores decreased significantly (P<0.05), the differencebetween two groups was significant (P<0.05), indicating that two groups in theimprovement of Parkinson’s disease.(kidney deficiency and blood stasistype).symptoms and signs are effective, and improve the degree of the treatmentgroup is better than that of control group;3.Each item response quality of life.SF-36.health survey in the two groups after treatment than before treatmentsignificantly increased the integration, at the same time, physiological function, physiological functions, physical pain, mental and social functions of projectintegration between the two groups was significant (P<0.05), indicating that twogroups in the improvement of Parkinson’s disease (kidney deficiency and blood stasistype) patients with physiological function, physiological function, body pain, generalhealth, energy, social function, role emotional and mental health programs areeffective, and the physiological function, physiological functions, physical pain,mental and social improvement function projects such as treatment group is betterthan pure Western medicine control group, there was no obvious advantage and thecontrol group in the general health, emotion and mental health projects.Conclusion: Guiling pa’an Wan plus Benserazide tablet can obviously reduce theParkinson disease (Deficiency of kidney and blood stasis type) of TCM syndromes,UPDRS3.0Rating Scale score, increase SF-36health survey points,and the clinicalcurative effect is obviously better than the pure western medicine treatment;At thesame time to improve the treatment of syndrome the UPDRS3.0Rating Scale score,SF-36health survey points can be improved to some extent, description of Guilingpa’an Wan can assist medicine very good to improve the symptoms of patients withParkinson’s disease, symptom and quality of life in the treatment of kidney deficiencyand blood stasis syndrome at. Shown in clinical application advantages. |