The Related Risk Factors Analysis Of Coronary Calcification Degree For Type2Diabetes Asymptomatic Patients

Objective: This paper aims at investigating the clinical characteristics and related riskfactors of abnormal coronary calcification for asymptomatic patients with type2diabetes. To make the type2diabetes patients with asymptomatic coronary anomaliescontrol the corresponding risk factors well, and delay the occurrence and developmentof acute cardiovascular disease.Methods:199patients with2type diabetes from endocrinology ward, cardiology wardand cadre ward were selected in the second affiliated hospital of Dalian medicaluniversity from June2013to March2014. The64row helical CT were used toenhance the coronary artery scanning, and the SPSS statistic software are used toanalyze the coronary artery calcification score. The selected risk factors for coronaryheart disease (CHD) include age, gender, duration of diabetes, BMI, smoking, familyhistory of positive rate, FBG, FCP, Fins,2hPG,2hC-P,2hINS, WBC, LYM, PLT,UACR, TC, TG, LDL-c, HDL-c, HOMA-IR, HOMA-β and HsCRP. All the patientsare divided into symptomatic and asymptomatic group according to chest tightness,shortness of breath and ectopic pain and other symptoms associated with coronaryheart disease. The asymptomatic group with neck vascular atherosclerosis coronarywas conducted enhanced CT examination. The asymptomatic type2diabetes groupwas divided into coronary artery calcification score>10points (65cases) and coronary artery calcification score <10points (45cases).And the type2diabetessymptoms group was divided into coronary artery calcification score>10points (50cases) and coronary artery calcification score <10points (39cases). The general lifeand biochemical index data were recorded, and clinical data was compared amongdifferent groups, the related risk factors of asymptomatic patients with type2diabeteswhich have abnormal coronary calcification were analyzed.Results:1. Type2diabetes asymptomatic group (artery calcification score>10) has highincidence compared with the type2diabetes symptoms group (artery calcificationscore>10).This is56.18%against59.09%.2. Asymptomatic type2diabetes mellitus merged group (calcification score>10)compared with type2diabetes symptoms merged group (calcification score>10),results showed that BMI, uric acid for asymptomatic group is lower than symptomaticgroup, the difference was statistically significant (P <0.05); UACR, high bloodpressure, neuropathy incidence rate for asymptomatic group is higher than that ofsymptomatic group, the difference was statistically significant (P <0.05).3.Asymptomatic patients with type2diabetes merged group (calcification score <10) compared with asymptomatic patients with type2diabetes merged group(calcification score>10), the pathogenesis for patients with calcification score <10groups is significantly shorter than those of diabetes calcification score>10, thedifference was statistically significant (P <0.05). The average age and UACR forcalcification score <10group tare much smaller than calcification score>10groups,the difference was statistically significant (P <0.05).4. Logistic regression analysis showed that age, diabetes duration, UACR are theindependent risk factors for type2diabetes asymptomatic patients with coronary arterycalcification abnormal (P <0.05). Regression model was Y=4.382+0.058X1+0.105X2+0.058X3, which can be used to evaluate coronary artery for patients.Conclusion:(1) Incidence of type2diabetes asymptomatic patients with coronary arterycalcification is higher. (2) UACR of type2diabetes asymptomatic patients is severer than type2diabetes symptoms patients. When the UACR <30mg/g, it has shown that thecoronary artery calcification appeared.(3) Age, diabetes duration and UACR are the independent risk factors for type2diabetes asymptomatic patients with coronary artery calcification anomalies. Earlyprevention, diagnosis and intervention treatment may prevent or delay the occurrenceand development of acute cardiovascular disease.