Value Of Procalcitonin In The Diagnosis Of Neonatal Sepsis

To determine the special diagnostic superiority of PCT test over CRP andWBC count test for the newborns with neonatal sepsis. Methods：We gathered46cases of inpatients diagnosed of neonatal sepsis in the Neonatal Department of DalianCentral Hospital from January2013to January2014and other50consecutivehospitalized uninfected neonates in the same period as control group. PCT and CRPconcentrations and WBC count were all measured simultaneously during thenewborns’ hospitalization. Positive standard: PCT>2μg/L; CRP>8mg/L;WBC>20×109/L. All data were analyzed by SPSS version13.0windows. Results：Allother variables had been thoroughly controlled. WBC count doesn’t have any valuediagnosing neonatal sepsis (P>0.05).However, there is a significant difference in PCTand CRP concentrations between both groups.(P<0.01).The sensitivity (87%)of PCTtest is exceptionally higher than that of CRP test (63%), but the specificity (87%)ofPCT test is slightly lower than that of CRP test(90%). In total, Youden index of PCTtest is exceptionally higher than that of CRP test. Conclusion： PCT is an extremelyvaluable biological marker in solid diagnose of neonatal sepsis.