Correlation Between Pulse Pressure And Left Ventricular Systolic Function And The Degree Of Coronary Artery Disease

Objective:To analysis of left ventricular systolic function and pulse pressure andcoronary artery disease degree of correlation.Methods:Through the200cases with complete data and coronary angiography wereretrospectively analyzed, the application of coronary artery lesions on coronarymorphology described measuring systolic blood pressure, diastolic blood pressure,pulse pressure, left atrial diameter (LAD), left ventricular end-diastolic diameter(LVEDD), left ventricular systolic diameter (LVESD) stroke volume (SV), cardiacoutput (CO), left ventricular ejection fraction (LVEF), blood and other data.Theselected patients with coronary heart disease and hypertension or not are divided intobasic data of patients comparing different groups (gender, age, heart rate), systolicblood pressure, diastolic blood pressure, pulse, blood and the severity of coronaryartery disease;Then follow the pulse pressure (PP)60mmHg grouped as boundaries,comparing each group of blood pressure, blood, coronary artery lesions, etc;Finally,coronary artery lesions are grouped compare left ventricular function.Measurementresults found for normal or near-normal distribution with mean±standarddeviation.Count data of significance test with χ2test, significant test measurementdata using t and (or) F test.These date were calculated using statistical softwareSPSS19.0which including systolic blood pressure, diastolic blood pressure, pulsepressure, left atrial diameter (LAD), left ventricular end-diastolic diameter (LVEDD),left ventricular systolic diameter (LVESD) stroke volume (SV), heart emission (CO),left ventricular ejection fraction (LVEF),blood.And then calculating the correlationbetween these date and the number of coronary artery lesions.Results:1.Patients overall data analysis showed that94cases of200patients withhypertension (47%), hypertension patients aged greater (P=0.016); double vesselcoronary artery disease prevalence and three in unconsolidated hypertensive patients(P <0.001); prevalence rate is lower than in patients with single-vessel disease inpatients with hypertension (P <0.001) unconsolidated; rapid heart rate in patients withhypertension, but the difference was not statistically significant (P=0.053); blooddifference was not statistically significant.2.As a result of PP to60mmHg boundaries grouping analysis showed thatpatients with PP≥60mmHg, age, SBP, DBP were significantly increased (P <0.05);prevalence of coronary artery single no difference between the two groups (P>0.05);double vessel disease prevalence in a weak difference between the two groups (P=0.049); prevalence of three-vessel disease in PP≥60mmHg were significantly higher (P <0.05); no difference in blood sex (P>0.05).3.By coronary artery lesions subgroup analysis showed that the three groups ofpatients left atrial diameter (LAD), the mean left ventricular end-diastolic diameter(LVEDD) increases with the severity of coronary artery disease increases, but thedifference was not statistically significant (P> O.05); mean left ventricularend-systolic diameter (LVESD) with the aggravation of coronary artery diseaseincreases, the difference between the three groups was statistically significant; strokevolume (SV), cardiac output () no CO between the groups was significant difference;mean left ventricular ejection fraction (LVEF) increases with an increase in theseverity of coronary artery disease and reduced the difference between the threegroups was statistically significant.4.Count coronary artery disease and correlation analysis of each index, Spearmancorrelation analysis showed that the severity of coronary artery disease with age (r=0.221P=0.028), SBP (0.216P=0.001), DBP (r=0.169P=0.002), PP (r=0.237P=0.029) were positively correlated; with LVEF (r=-0.063P=0.001) werenegatively correlated; and red blood cells, white blood cells, platelets, hematocrit, CO,SV, LVSED and so no correlation.