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Anterior Circulation Infarct Formation Of Collateral Circulation And Clinical Analysis Of Related Factors

Posted on:2015-10-19Degree:MasterType:Thesis
Country:ChinaCandidate:D B YaoFull Text:PDF
GTID:2284330422476763Subject:Neurology
Abstract/Summary:PDF Full Text Request
Objective:Application of digital subtraction angiography preliminary analysisof the Anterior circulation artery stenosis in patients with cerebral infarction due todistribution, degree of stenosis, collateral circulation to assess the situation,And therelationship between the collateral circulation and nerve function defect for prelimin-ary analysis,to further explore the relationship between Anterior circulation arterystenosis or occlusion of collateral circulation in patients with cerebral infarction andclinically relevant factors。Methods:Choose from January2012to January2014in the First AffiliatedHospital of Nanchang University with acute ischemic stroke and have the internalcarotid artery or middle cerebral artery lesions, ready for further treatment (arterialbypass or internal carotid artery stent Internal carotid artery stripped) of112patientsas the research object。All enrolled patients were perfect general data acquisition,Improve the head MRI scan and carotid artery ultrasound, DSA and other imagingstudies,Improve blood sugar, blood lipids, homocysteine and other biochemicaltests,Be NIHSS score,To have collateral circulation of52patientsas as theexperimental group,without collateral circulation of60patients as control group,Comparison between the two groups of vascular stenosis, degree of stenosis andnerve function defect degree,And the impact of risk factors on the establishment ofcollateral circulation。Using SPSS19.0statistical software for data input and output,With P<0.05was considered statistically signi-ficant。Results:①Of all of the112patients enrolled male66cases, female46cases,The youngest37years old,, the biggest80years old,mean age of56.90+11.39, nosignificant difference between male and female。②Among the112cases, there were130vessel lesions,Which intracranial vascular lesions86,44extracranial vasculardisease,88stenosis, occlusion in42,Distribution of15common carotid arteries,internal carotid artery lesions there are48, there are67middle cerebral artery。of allthe52cases of collateral circulation,the anterior communi-cating artery open up to20,12cases posterior communicating artery open。both the anterior and posterior communicating artery open8cases,the ophthalmic artery open four cases,Leptomeningeal channels open in8cases。③Narrow degree and the position betweentwo groups have the difference,(P <0.05), with the increase of degree of stenosis,collateral circulation increase,④NIHSS scores between the two groups,NIHSSscores with collateral circulation was significantly lower than those without collateralcirculation, there are differences, P <0.05,Collateral circulation improve the clinicalsymptoms of cerebral infarction⑤To the risk of Significant factors by multivariateLogistic regression analysis,Showed that the hypertension promote the formation ofcollateral circulation high blood glucose, blood lipids, homocysteine、etc are notconducive to the formation of collateral circulation。Conclusion:1、When anterior circulation infarct artery stenosis occurs inintracranial,And more common in middle cerebral artery lesions2、Open collateral circulation associated with cerebral artery stenosis degree,degree of stenosis is heavier, collateral circulation open more fully3、Collateral circulation has a protective effect to ischemic brain tissue。canimprove the clinical symptoms of cerebral infarction, reducing infarct volume.4、the formation of collateral circulation,the first open is primary collateralcirculation,the main open is manterior communicating artery5、The formation of collateral circulation is affected by many factors,and thehigh blood sugar,smoking,high blood lipids,high homocysteine etc. are notconducive to the formation of collateral circulation.。...
Keywords/Search Tags:Anterior circulation, Cerebral infarction, collateral circulation, Clinical Analysis
PDF Full Text Request
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