| Objective:Using multivariate linear regression analysis, variance analysis, Spearman rank correlation analysis to investigate102cases of drug-addicting patients with HIV/AIDS in Hunan province in TCM syndrome distribution characteristics, quality of life as well as the relationship between them, to guide Chinese medicinal syndrome differentiation and treatment of this population.Methods:Traditional Chinese medicinal prevention and control of AIDS’ research center of Chinese Academy of Traditional Chinese Medical Sciences makes the cross-sectional investigation of102cases of drug-addicting patients with HIV/AIDS in Hunan province by the HIV/AIDS syndrome questionnaires (the cases related to the increase of drugs) and MOS-HIV quality of life scale. First of all, the collection, the grading type, and the frequent statistics and descriptive analysis of the information of TCM symptoms, signs, tongue, pulse condition, the condition of drugs’use, quality of life are done. Secondly, all the diversity of regression analysis of the factors affecting the quality of life is made to define the major factors for the drug-addicting patients with HIV/AIDS; then the analysis of variance is used to analyze the five main TCM syndrome types and quality of life scores and the relationship between the dimensions’scores; finally,the Spearman rank correlation analysis is used to explore the correlations among the quality of life scores, each dimension’ score and TCM syndrome’total credit score.Results:Among the102cases of drug-addicting patients with HIV/AIDS in Hunan province, the main common clinical symptoms which are more than70%include amnesia, insomnia, agitation, lack of power, waist and knee pain, mental fatigue, xerostomia, cough, depression,dizziness, palpitation, cough, depression, with the symptoms of systemic symptom, heart and head, liver and gallbladder. The liver Qi stagnation and hyper-fire type is main of the types of syndrome differentiation in the asymptomatic period, with31cases, accounting for30.39%, followed by deficiency of both Qi and blood type with24cases, accounting for23.53%and phlegm-heat disturbance with13cases, accounting for12.75%; deficiency of Qi and Yin,lung and kidney is given priority to in the AIDS period with14cases, accounting for13.73%, followed by the spleen and kidney deficiency pathogenic dampness block with8cases, accounting for7.84%. The rest of the yuan qi deficiency failure and kidney Yin desiccation, poison indicating lung phlegm and hot accumulation each accounts for4cases, each for3.92%, liver by wind fire and wet-poison accumulation with2cases, accounting for1.96%, qi deficiency and blood stasis and poison lag, qi depression phlegm blood stasis,1case each, accounting for0.98%. The investigation and study found the drug-addicting patients with HIV/AIDS in Hunan province have the low quality of life, and the BMI and CD4counts are the important factors affecting the total score of life quality scale. Also, there is the difference of the quality of life at different syndrome types in patients.Conclusion:102drug-addicting HIV/AIDS’patients in Hunan province have highly frequent clinical symptoms of the cardio-cerebral department such as amnesia, insomnia, agitation; the card type of the most distribution is liver Qi stagnation and hyper-fire type; the quality of life is overall low; there is the difference of quality of life at patients of different syndrome types. |