More Clinical Research Of Traditional Chinese Medicine Treatment Of Colorectal Surgery Center

Objective:To Evaluate the clinical efficacy and safety of standardization scheme of postoperative TCM treatment in colorectal cancerMethods:Divided the colorectal cancer patients after surgery form five center into treatment group and control group, both groups accept6cycles of modified FOLFOX chemotherapy regimen commonly used in China, the treatment group accept the TCM treatment according to the standardization scheme of postoperative TCM treatment, the control group, no longer receiving systematic TCM treatment, observe the two groups and followed up for record progression-free survival (PFS), median survival time (MST), quality of life, toxicity.Results:The median PFS of treatment group and the control group were36.6months vs.28.2months,(P<0.05). The MST of treated group did not come, the MST of control group was42.5months,(P>0.05). Further analysis by stratified the result with clinical stage, the MST of two groups from the patients of stage II were not come,(P>0.05); the MST of two groups from the patients of stage III were38.8months vs.27.6months,(P<0.05), the MST of two groups from the patients of stage IV were19.5months vs.6.7months,(P<0.05). The treatment group has advantages in improve the quality of life and reduce the incidence of adverse reactions than the control group (P<0.05).Conclusion:the colorectal cancer patient accept the TCM treatment can prolong the survival time better than chemotherapy alone, especially in advanced patients, It can also improving the quality of life and reduce the incidence of adverse reactions better than chemotherapy alone.