| Background:Currently, multi-drug resistant Organism (MDRO) infection prevention and control is faced with enormous difficulties and challenges in hospital infection management. Infection of MDRO not only increase the suffering of patients,prolonged hospitalization, and increasing medical expenses, but also bring great difficulties to the treatment of patients with, or even no drugs available, This kind of situation seriously affecting the quality of medical care, worsely endanger the patient’s life. The consequences will be extremely serious, and the hospital and the community will meet a tremendous negative impact. So MDRO infection control and prevention is more important than treatment.. In recent years, the Ministry of Health issued sume guidelines for the prevention and control of multidrug-resistant, but the control effect of specific control measures such as MDRO patient isolation, hand hygiene management, rational use of antimicrobial drugs, environmental disinfection isolation of implementation, and MDRO are need to detailed evaluation.Purpose:Research objective to understand MDRO infection occurrence in a hospital inpatient of Shandong Provincethe.risk factors related to infection. The compliance of prevention and control measures. through the promotion of integrated control measures implemented, could reduce hospital incidence of multi-drug resistant hospital infections or no and evaluate the control effect; through monitoring of multiple drug-resistant, summed suitable MDRO hospital infection prevention and control measures, to provide a scientific basis for clinical multidrug-resistant nosocomial infection prevention and control.Materials and Methods:A retrospective collection of January1,2011to December31,2011multi-resistant hospital patient’s basic information, as the A group. Prospective Investigation from1January2012to31December2013multi-resistant hospital patient information, as the group B. Adopt targeted interventions in group B patients, including multi-drug resistant strengthen propaganda training. enhance medical staff hand hygiene, take proper quarantine measures, the rational use of antimicrobial drugs and other series of comprehensive control measures. Then the infection status of group A and group B were analyzed to evaluate the efficacy of the hospital infection control。Main Results:January1,2011to December31,29,302cases were treated in hospital,773cases were monitored among multi-drug resistant infections and colonization, accounting for2.63%of hospitalized patients at the same time.497cases were community-acquired infection of this773cases, accounting for64.29%,276cases of nosocomial infection, accounting for35.71%, Comparison between the two,The more community infection majority..FormJanuary1,2012to December31,2013,83,811inpatient cases were treated in hospital, monitoring of in patients with1,534cases with multi-drug resistant infections and colonization were detected,accounting for1.83%of hospitalized patients. There were community-1187cases among1534cases of multi-drug resistant infections patients, accounting for77.38%,347cases of nosocomial infection, accounting for22.62%, more community infections. In the two group,MDRO patients in the distribution department, specimen source, the site of infection, the detection of pathogens as well as risk factors all have significant differences. Through targeted interventions, MDRO hospital infection rates decreased from0.94%of group A to0.41%of group B, infection rates decreased significantly. Aware rate of knowledge about multi-resistant bacteria from73.29%to99.54%, MDRO infection were reported rate from12.68%to12.68%Antimicrobial usage and combination therapy, as well as prophylactic antimicrobial usage gradually decreased,Clinical therapeutic antimicrobial usage reduced year by year from59.59%to30.0%, therapeutic antimicrobial agents specimens sent rate increased year by year, from12.74%rise to50.04%.Conclusions and recommendations:MDRO hospitalized patients with more serious situation,and this has become a major challenge faced by clinical work. Strengthen MDRO targeted surveillance of hospital infection by taking comprehensive intervention measuers can significantly reduce the infection rate of multi-drug resistant in hospital, the medical staff to improve knowledge and awareness of multiple drug-resistant,infection reported rate significantly increased.hand hygiene compliance, accuracy greatly improved, more rational use of antimicrobial agents. Effective control of MDRO hospital infection, this need to establish and improve the multi-resistant hospital management organization, multi-sectoral, multi-department collaboration with each other, while there is a strong need for information systems as a support, and a follow-up supervision and management of maturing and incentive system as a safeguard. |
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