A Report Of55Cases Of Mediastinal Germ Cell Tumors

Objectives:According to the statistic analysis of the clinical data of patients with primary mediastinal germ cell tumors, we can investigate the epidemiology of the disease and find that a variety of symptoms, signs caused by the disease,which will definitely contribute to the study treatment of the disease so as to improve the diagnosis and treatment accordingly.Methods: I collected the clinical Statistics from2004to2013about thoracic surgery including55cases of primary mediastinal germ cell tumors inpatients. To convince my point, I compare and analyze these statistics.Results: I got55cases, including30males whose average age was26.5years;25female whose average age was30.12years old. Among these patients, benign teratoma is47cases, accounting for85.45%of all patients, pathologically confirmed The rest two cases of immature teratoma are pathologically confirmed. Pathologically confirmed cases of seminoma ends with one case, the pathological cases containing seminoma germ cell carcinoma keeps same, pathologically confirmed cases of germ cell cancer is also one, while pathologically confirmed cases of endodermal sinus tumor account for2cases, pathological cases containing both teratoma and endodermal sinus tumor components is one case. Cancer patients are all male. Tumors were located in the anterior mediastinum. Surgical treatment:Anterolateral incision surgery is24cases, median sternotomy incision is23cases, posterolateral incision is3cases, patients underwent video-assisted thoracoscopic (VATS) surgery in three cases, two cases take no operation. The number of Patients treated with simple excision of the tumor is43cases; patients treated with same type of tumor resection including wedge resection of lung involvement is9; the number of partial tumor resection only has one.Conclusion: Most of Patients with Primary mediastinal germ cell tumors are young whose age ranges from15to40. Tumors are usually found in the anterior mediastinum. Most of tumors are benign teratoma,There is no obvious difference with the gender of patients. Histologically confirmed that malignant cases is few. patients are usually male with short duration. Now the clinical diagnosis of the disease mainly depends on chest X-ray and CT examination. Surgical resection now is the only effective treatment for benign germ cell tumors.Early diagnosis and early post-surgery therapy is better, which can ensure higher resection rate. When it comes to the complete resection of the tumor, the prognosis is good because there is few malignant germ cell tumor samples and lower removal rate. The prognosis is not that satisfying,we now are unable to prove that surgery is more effective than chemotherapy.