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MR Imaging Feature:Superficial Siderosis Of The Central Nervous System

Posted on:2015-03-22Degree:MasterType:Thesis
Institution:UniversityCandidate:Hasan AkhtarFull Text:PDF
GTID:2254330431453262Subject:Radiology and Nuclear Medicine
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Objective:To study the imaging features of superficial siderosis. Methods:MRI Applications is on randomly done on patients with trauma, post-op and the unknown etiology in period of more than2years by using.3.0T MR system (Verio, Siemens Medical Systems, Erlangen, Germany). Sequence is as follows:axial T1WI (TI/TR/TE:823/1900/9), T2WI (TR/TE:6000/96), T2-FLAIR (TI/TR/TE:2140/6600/94), T2*WI (TR/TE:620/20), sagittal T1WI, T2WI and MR cisternography (TR/TE:1500/224).Results:Superficial siderosis is a rare chronic neurological condition characterized by bilateral sensorineural hearing loss, Cerbellar ataxia and myleopathy. It is caused by haemosiderine deposition in the brain and spinal cord resulting from chronic subarachnoind hemorrhage. Diagnosis is confirmed by the presence of hypointense area on T2weighted MRI images. The subtlety of the MRI changes potentially delays diagnosis of SS. Accurate clinical assessment coupled with the correct imaging technique offers the highest chance of securing a diagnosis of superficial diagnosis. Considering the central nervous system containing hemosiderin deposition disease diagnosis is very important. In order to avoid irreversible damage to the central nervous system, even the subtle signs and SS-related MRI can not be underestimated. SS imaging performance is the manifestation of subarachnoid hemorrhage. Superficial siderosis is a radiological or pathological diagnosis of hemosiderin deposition in the brain and spinal cord that is caused by chronic subarachnoid hemorrhage. The classic triad of symptoms is bilateral sensorineural hearing loss, ataxia, and myelopathy, and the T2MRI pathognomonic findings are rims of hypointensity around the brainstem, cerebellum and spinal cord. The most common causes of the chronic subarachnoid hemorrhage that lead to superficial siderosis include CNS tumors, head and neck trauma, and arteriovenous malformations, although an occult source is unidentified in over a third of cases. When discovered early the condition can potentially be treated by ablating the source of bleeding, but the natural course of superficial siderosis is a progressive neurological decline. Conclusion:superficial siderosis of central nervous systemis a rare disease and MRI scan, especially T2WI has important diagnostic value of it.
Keywords/Search Tags:Surface iron deposition disease, central nervous system, sensorineural hearingloss, fluid-attenuated inversion recovery sequence, subarachnoid hemorrhage
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