Objective:To investigate the effects of oral nutritional repletion and active exercise on quality of life in stable COPD patients.Methods:Prospective, randomised study. Ninety-eight patients with stable COPD were randomdly divided into malnutrition hierarchical classification.General therapies were both taken in two groups,while oral nutritional repletion and active exercise training were given to patients in experimental group only. Twelve weeks was taken as a course of treatment. The nutritional status of all patients were valuated before and after treatment by subjective global assessment of nutritional status(SGA).The quality of life of all patients were valuated before and after treatment by COPD assessment tool (CAT).The BMI,TSF,MAC and ALB in all patients were determined before and after treatment. Results:There were no signifficant difference between two groups before treament(P>0.05). After12weeks of follow-up, the total scores of CAT of the patients in the experimental group were markedly lower than those before treatment(P<0.05),also obviously lower than in the control group(P<0.01). The BMI,TSF,MAC and ALB of the patients in the experimental group were markedly higher than those before treatment(P<0.01),also obviously higher than in the control group(P<0.01). The SGA also better than in the control group(P<0.05).The BMI.TSF, ALB,CAT of the patients in the control group had no signifficant difference than those before treatment(P>0.05),but the MAC was markedly lower than those before treatment(P<0.05)Conclusion:Oral nutritional repletion and active exercise can improve the quality of life and ameliorate their nutritional status in stable COPD patients. |