Objective:Through clinical efficacy observed before and after the treatment of angina pectoris (blood stasis type) by Xueshuantong capsule, to evaluate the efficacy and safety of treatment of angina, providing a basis for clinical use.Methods:64patients with angina patients (blood stasis type) were randomly divided into treatment group and control group,32cases in each group.The treatment group taking the Xueshuantong capsules, two capsules one time, three times a day, taking a total of8weeks;the control group were treated by Ginkgo biloba capsules,two capsules one time, three times a day, taking a total of eight weeks.ECG efficacy,angina points,TCM symptom scores,experimental Duke treadmill score,nitroglycerin tablets to stop reducing rate, the efficacy of individual symptoms were observed after4and8weeks’treatment.Differences situation around safety indicators and efficacy indicators comparing two groups of patients treated.Results:l.ECG analysis before and after treatment:After treatment,both groups can effectively improve the level of ECG,the total effective rate in the treatment group is80.65%,while the total effective rate of the control group is64.52%(P<0.05).The results show that:The ECG improvement effect in the treatment group is better than the control group.The difference is significant,with statistically significant.2.Compares the angina points,TCM symptom scores before and after treatment:there is no significant difference in the data of the angina points-. TCM symptom scores before treatment(P>0.05). After4weeks of treatment,the points significantly lower than those in the two groups before treatment(P<0.05).After8weeks of treatment, the scores decreased significantly compared with the degree of integration,statistically significant difference.3.Compares Exercise treadmill test Duke score before and after treatment:No significant differences in pre-treatment score Duke before treatment(P>0.05).Duke score increased significantly than before treatment after4weeks treatment(P<0.05),and more significant increase in the treatment group than the control group. After8weeks of treatment,Duke score increased significantly compared with the extent of before(P<0.01),and treatment group increased significantly more (P<0.05).4.Nitroglycerin tablets to stop reducing rate,the efficacy of individual symptoms analysis before and after treatment:After treatment,nitroglyceriri tablets to stop reducing rate is90.32%in the treatment group,the control group is70.97%(P<0.05).The efficacy of individual symptoms is93.55%in the treatment group,the control group is77.42%(P<0.05).Two indicators of efficiency observed significant differences in the treatment group than the control group, the difference was statistically significant data results.Conclusions:l.Xueshuantong capsules can significantly reduce the clinical symptoms of angina,improve TCM symptoms performance,reduce the incidence of individual symptoms.2.Xueshuantong can significantly improve the level of the patient’s electrocardiogram,elevated the Duke score of exercise treadmill test,reduce the dose of nitroglycerin.3.In this clinical observation process,The safety index was no clinically significant change.Xueshuantong angina significant adverse phenomenon does not appear,no significant side effects. |