The Time-series Studies Of PM2.5and The Number Of Admissions For Acute Myocardial Infarction

Objective: Along with the rapid development of economy andurbanization, air pollution is more and more intensified, atmospheric hazeoccurs frequently, making people pay more and more attention to the impactof which PM2.5particulate pollutants bring about on health. PM2.5is a fineparticle matter also known as particulate matter can go directly to the alveoliof the lungs which aerodynamic diameter smaller than2.5micrometers.Although the composition of the atmosphere of PM2.5in small amounts,however，its characteristic，such as small particle size, large specific surfacearea, and containing large amounts of toxic and hazardous substances,strongly absorbing organic matter, heavy metals and other substances in theatmosphere, long residence time and conveying distance in the atmospherethat can vary with human breath into the body, or even directly into the alveoliand the blood, which led to a variety of diseases, so it has a significant impacton atmospheric environmental quality and human health. In recent years, themorbidity and mortality of cardiovascular diseases, accounting for the totalpopulation proportion of morbidity and mortality increases year by year, andthe younger age trend appear, thus, PM2.5become a hot word, and the hazardof PM2.5for human health has received more and more attention.This paper discusses the relevance and the time-series studies betweenPM2.5and acute myocardial infarction admissions in Shijiazhuang, toprovides realistic basis for the prevention and control of atmospheric pollution,formulate relevant environmental health standards, take protective measurescomply with the local state of the environment, improve the health level andthe protection of vulnerable populations.Methods: The total number of patients with acute myocardial infarctionwho visit at the Second Hospital of Hebei Medical University in Shijiazhuang from January1,2013to December31,2013are collected，as well as dailyPM2.5research monitoring data of ambient air quality announced byShijiazhuang environmental protection department, these data were entered toestablish a database with Microsoft Excel2003,first, to collate, logic errorchecking and imputation of missing values for PM2.5concentration and casesof acute myocardial infarction with SPSS13.0software, Secondly, timedistribution were described respectively then the variables from the regressionmodel were created, and PM2.5lag should be into the consideration, Thirdly,analysis the correlation between PM2.5concentration and the number ofadmissions for acute myocardial infarction.Results: During the study period, the total numbers of acute myocardialinfarction patients are1229, daily average concentration of PM2.5researchmonitoring data of ambient air quality announced by Shijiazhuangenvironmental protection department is265.78μg/m3,auto-regression modelshows that PM2.5levels were positively correlated with the incidence of acutemyocardial infarction, the incidence increased with the increasingconcentration, and there is a certain lag in the correlation, the3day lag effectis the most significant.Conclusions:PM2.5concentration in Shijiazhuang were positivelycorrelated with the incidence of acute myocardial infarction, and the incidenceincreased with the increasing concentration, and appears a certain lag, the3day lag effect is the most significant.