The Retrospectively Analysis Of Eariy Drug-eluting Stent Thrombosis

Objective:Through the analysis of finishing percutaneous coronary interention (PCI)after early drug-eluting stents (DES) thrombosis (0~30days) in patients withclinical data and Coronary angiography results,to explore early drug-elutingstent thrombosis related risk factors.Methods:Retrospective analysis of our hospital on January1,2012to December31,2013with drug-eluting stent the interventional treatment of4694patients withcoronary heart disease, including42patients with occurrence of early stentthrombosis, using multiariable Logistic regression model to analyze itsclinical data, coronary angiography results, with the stent placement.Result：1：In42patients occurred early stent thrombosis after coronary stentimplantation (incidence0.9%),Including9cases of acute stentthrombosis（incidence0.3%),31cases of subacute stent thrombosis（incidence0.6%），Confirmed by coronary angiography，triple-vessellesions in26patients（62%），double-vessel lesions in8patients（19%）single-vessel lesion in18patients（19%），Left anteriordescending branch lesions in26patients（62%），Multiple stents（>3）in8patients，early stent malapposition in2patients；Cardiacinsufficiency with low blood pressure in24patients；B2/C type lesionsaccounted for67%.2：Multiple factors regression analysis shows advanced age、acute coronary syndrome、cardiac insufficiency、the high level of fibrinogen、Longlesions、Long stent are independent risk factor for early stentthrombosis.PCI therapy in patients with acute myocardial infarctionoccurred early stent thrombosis risk was4.849times than that inpatients with unstable angina pectoris.3: Underwent emergency percutaneous coronary interventional treatmentfor patients with18cases,15patients were rescued successfully anddischarged from hospital.Rescue invalid death in27patients(Casefatality rate64%).Emergency interventional therapy again is the firstchoice of treatment of early stent thrombosis.Conclusions：1：Early stent thrombosis are related to advanced age, acute coronarysyndrome, cardiac insufficiency，high level of fibrinogen, longlesions, long stents.2: The standardization and individualization of interventional treatmentand Strengthen the PCI perioperative period antiplatelet therapy is one ofthe important measures to prevent early stent thrombosis, In patientswith stent thrombosis has occurred can increase the success rate ofrescue.3：Emergency interventional therapy again is the first choice of treatmentof early stent thrombosis.