The Analysis Of Traditional Chinese Medicine Differentiation Of Sysmptoms And Signs For Hypertensive Patients With Cardiac Structure Damage In Relation To QT Dispersion

Objective The aim of the study was to assess the connection between the QT dispersion (QTd) and the Traditional Chinese Medicine (TCM) differentiation of sysmptoms and signs in hypertensive patients with cardiac structure damage, by investigating the electrocardiogram (ECG)、echocardiography (UCG) and other clinical data。Methods80cases were selected from admitted patients in2012,32were hypertension in level2,48were hypertension in level3, including32patients with left atrial hypertrophy (LAH),48patients with left ventricular hypertrophy (LVH)。 We also investagited those patients with other factors, such as39patients with hyperlipidaemia (HLP),35patients with congestive heart failure (CHF, NYHA Ⅰ～Ⅱ)。the electrocardiographic parameters such as QTd, QTcd were manually measured from standard12qead ECGs. Other factors as biochemical indices, echocardiogram results were recorded at the same time. Meanwhile we assessed the connection between the QTd and the TCM differentiation of sysmptoms and signs in those patients.Results By the study on the related factors to QT dispersion, the heart rates appeared to be positively correlated with QTd (P<0.01). The mean QT dispersion was significantly higher in patients with hypertension compared to those with normal persons(P<0.01), and patients in hypertension level3were more obvious (P<0.05).When grouped by cardiac structure damage、cardiac function、hyperlipidaemia, we found that LVH and CHF can increase the QTd、QTcd more obviously(P<0.05).according to TCM differentiation of sysmptoms and signs, QTd、QTcd in the patients of inclination to deficiency were higher than those of inclination to excess (P <0.01)Conclusion Within the heart rate (58bpm-98bpm) we studied in this test, we found that QTd is related to heart rate positively.But we can get rid of this by take advantage of the formula named Bazett.QT dispersion is significantly increased in the hypertensive patients with cardiac structure damage, especially in the patients with LVH, CHF, suggests that myocardial hypertrophy, and cardiac decompensation can increase the aonormal ventricular bipolar, which may lead to a high risk of malignant arrhythmia.By the TCM differentiation of sysmptoms and signs in hypertensive patients,we see that the syndromes in deficiency group have no obvious regularity,but in excess group,the QT dispersion in the Tanshiyongsheng syndrome is higher than the Ganhuokangsheng syndrome.the TCM differentiation of sysmptoms and signs in hypertensive patients can transform from excess to deficiency, Along with the increase of QTd。So, QT dispersion is an objective indicator when measure the TCM differentiation of sysmptoms and signs for hypertensive patients.