The Value Of CT Spectral Imaging For Diagnostic Of Central Lung Cancer And Metastatic Lymph Nodes

Objective：By measuring and analyzing central lung cancer the different single energytumor and metastatic lymph nodes CT values and attenuation curves, iodine content,water content, and to explore gem spectroscopy CT imaging of different pathologicaltypes of central differential diagnosis of lung cancer and metastatic lymph nodes.Methods：Collection and retrospective analysis of the First Affiliated Hospital ofDalian Medical University from October2011to October2012in our hospital afterspectroscopy CT imaging in the diagnosis confirmed by pathology of central lungcancer with lymph node metastases spectroscopy imaging.Small cell lung cancer in9cases,8cases of adenocarcinoma,12cases of squamous cell carcinoma, small cell lungcancer metastatic lymph nodes in8cases, five cases of adenocarcinoma metastaticlymph node, squamous cell carcinoma metastatic lymph node9.The All images analysisand measurement in professional workstation on the GE AW4.5of the energy spectrumof CT scan arterial phase images sent to the GSI Mono the spectrum imaging browsersoftware (GSI Viewer).Central lung cancer, at the maximum cross-section of the massregion of interest (region of interest, ROI); shortest diameter greater than1cm lymphnode, the same region of interest in its largest cross-section.Measuring the energy level of each region of interest (including the40-140KkeV,10keV interval) CT value, an iodine concentration and waterconcentration; spectroscopy curves obtained for each region of interest at the same time,as a reference point to40keV and100keV calculated-spectroscopy slope of the curve,i.e. the slope=(40keV CT the value-100KeV the CT value)/60.Results: Mixing energy image, single-energy image and iodine-based image threeimage lesions can more clearly displayed (see Figure1-6); different pathological typesof lung cancer and metastatic lymph nodes in different KeV different degree ofattenuation,attenuation curves behave differently. Small cell lung cancer and adenocarcinoma, squamous cell carcinoma indifferent KeV difference between CT values were statistically significant,adenocarcinoma and squamous cell carcinoma only40-50KeV between the CT valuedifference was statistically significant.Small cell lung cancer metastatic lymph nodesand squamous cell carcinoma metastatic lymph nodes only in the40-60KeV betweenCT value difference was statistically significant, of adenocarcinoma metastatic lymphnodes and squamous cell carcinoma metastatic lymph nodes there were only between40-50KeVsignificance, small cell carcinoma metastatic lymph nodes withadenocarcinoma metastatic lymph nodes spectrum attenuation curve was notstatistically significant.No statistical significance between different tumors andmetastatic lymph nodes water content. Small cell carcinoma, adenocarcinoma iodinecontent was significantly higher than that of squamous cell carcinoma, small cellcarcinoma and adenocarcinoma iodine content was not statistically significant. Smallcell carcinoma metastatic lymph nodes, of adenocarcinoma metastatic lymph nodes thansquamous cell carcinoma metastatic lymph nodes high iodine content, with statisticalsignificance. Small cell carcinoma metastatic lymph nodes and adenocarcinomametastatic lymph nodes iodine content was not statistically significant.Conclusions：1.CT imaging spectroscopy as a new, noninvasive means of different pathologicaltypes of lung cancer and lymph nodes metastasis single energy analysis, iodine-basedanalysis and other means research, clinical diagnosis and treatment provides a more awealth of information.2.Through the energy spectrum of CT imaging and material separation technology,energy spectrum CT can carry out a more detailed assessment of lung cancer andenlarged lymph nodes, but also provides a direction for the inspection of other diseases.