Analysis On The Clinical Features Of1093Cases Of Gastric Cancer

Objective: Through to retrospective analysis the gastric cancer patients of da lianmunicipal central hospital which is confirmed by gastroscope and Surgery of pathologybetween January12007and December312007, analysis the clinical and pathologicalcharacteristics, diagnosis and prognosis outcome,to find out the clinical pathologicalcharacteristics and laws of gastric cancer in Dalian.Methods: we described the follow information of all cases by differentyears， such asage, gender, disease location, endoscopic morphology,histological type, clinicalsymptoms, concomitant diseases, family history,treatment, whether recurrence anddeath. Divisions of the year, compare different years gastric cancer gender compositionratio, high risk and macroscopic classification etc. Characteristics. In addition to allgastric cancer cases was divided into7groups according to age:≤29,30~,40~,50~60~,70~,≥80, with reference to the literature at home and abroad will age <50asyoung and middle-aged group,age≥50as elderly group. Comparison of different gender,age distribution and degree of pathological differentiation in patients with gastric cancer,so simple to reflect the characteristics of clinical pathology in patients with differentgender, age.Results:1. The mean age,62.5years,1093cases of gastric cancer patients. High-risk aged70~79, accounting for30.92%. All gastric cancer patients accounted for72.9%of the menand women account for27.1%, men’s and women’s gender composition ratio was2.69:1.2. All parts of the distal rate was highest, accounting for53.52%, with age (<80years)the incidence of gastric cancer appeared rising trend, after the age of80or higher, theincidence is declining, in gastric antrum is significant.3. the incidence of gastric cancer patients in our hospital distribution site was nosignificant difference in2007-2011. 4. Women’s stomach body stomach cancer incidence of a disease is significantly higherthan male (P <0.05), the distal gastric cancer incidence was significantly less than men(P <0.05).5. The most common pathological classification in adenocarcinoma (73.65%), and inlow differentiated adenocarcinoma is the most frequent (39.80%); in elderly groupmoderately differentiated adenocarcinoma and poorly differentiated adenocarcinomaincidence was significantly higher than in young and middle-aged group (p <0.05),while the incidence of signet ring cell carcinoma and other types significantly below theyoung and middle-aged group (p <0.05).6. Male patients with moderately differentiated adenocarcinoma and other types ofcancer incidence was significantly higher than women (P <0.05), while the incidence ofsignet ring cell carcinoma significantly lower than female (P <0.05).7. The microscopic morphology of most common Ⅱ type limitations ulcer type(59.9%), men with type Ⅰ uplift rates significantly higher than that of female (P <0.05), Ⅳ diffuse infiltrating type women have lower rates (P <0.05).8. In this study,1093patients with gastric cancer early gastric cancer in26cases,accounting for2.38%of all patients with gastric cancer9. Limitations in the elderly group Ⅱ ulcer (p>0.05) and Ⅳ type diffuse infiltratingtype (p>0.05) was lower than those of young and middle-aged group, the incidence oftype Ⅲ infiltrating type ulcer incidence of relatively young and middle-aged group(p>0.05), all did not reach statistical difference.10. Gender and gastric cancer site, histological type and microscopic morphology werecorrelated with a correlation coefficient0.148,0.163,0.107; Age and type of pathology,microscopic morphology were correlated, the correlation coefficients were0.267,0.263.These correlation coefficients sided test confirmed the correlation coefficient wasstatistically significant (p <0.05).11. See more clinical symptoms of abdominal pain/abdominal distension (79.04%),followed by the thin and/or loss of appetite (5.21%), difficulty swallowing (4.67%),bleeding (10.15%), etc.12. Merge the most common chronic disease in hypertension (18.02%), followed bydiabetes (9.51%).13. The digestive tract obstruction is one of the most common complication (18.11%),followed by gastrointestinal hemorrhage (16.28%) and perforation (1.37%), and jaundice (0.18%).14. Line1093cases of colorectal cancer patients, simple surgical treatment of523cases(47.85%),288cases (26.35%) surgery combined with other auxiliary treatment. In the811patients who underwent surgical treatment of gastric cancer,465cases of radicalresection is the most common (57.33%).15. Gastric cancer metastatic sites, liver metastasis is the most common,11.3%underwent surgery patients relapse after2months to5years.16.176deaths in136cases of death within one year after discharge, accounted for77.3%of all death.Conclusion:1. The high incidence of gastric cancer in age from70to79years, male occurred.2. The distal gastric cancer happens, along with the age growth (<80years of age)incidence appeared rising trend, or the80-year-old rates continue to drop.3. The incidence of gastric cancer site no significant change in5years.4. Women gastric gastric body multiple; male gastric cardia, gastric, stomach angle,antrum, pylorus, residual stomach fat.5. Low differentiated adenocarcinoma of the most common pathological types in gastriccancer. Moderately differentiated adenocarcinoma and middle-low differentiationadenocarcinoma in the elderly population, signet ring cell carcinoma and other kind ofhappens in young and middle-aged people.6. Multiple differentiation adenocarcinoma in men, women more signet ring cellcarcinoma.7. In advanced gastric cancer with Ⅱ limited ulcer most often. Ⅰ type uplift typeoccurs in men, Ⅳ type diffuse infiltrating type occurs in women.8.The incidence of early gastric cancer is low in5years.9. The middle-aged and old patients with multiple Ⅲ infiltrating ulcer gastric cancer.10. High blood pressure, diabetes is the most common chronic merger disease of gastriccancer patients.11. The most common complications in the digestive tract obstruction, family history ofcancer in the stomach more see, give priority to in order to send out.12. Surgery is still the main treatment for gastric cancer.13. Transfer part of the liver is the most common cancer of the stomach. Recurrence isan important factor affecting the prognosis of gastric cancer. 14. This study most of the deaths occurred in less than one year after the diagnosis ofgastric cancer..