Clinical Of Research The Highrisk Factors Of Apnea Of Premature Infant

PurposeThe aim of the study is to explore a variety of related factors of apnea of premature(AOP) and to summarize the high-risk factors through case-control analysis. The resultswill provide new idea to elucidate the prevention and to reduce or avoid the complicationsof AOP.MethodsTo retrospectively analyze the103cases of Apneas admitted by the No.88Hospital ofthe Chinese People’s Liberation Army from January2011to December2012, and the103cases of Non Apneas admitted by the No.81Children’s Hospital of the Chinese People’sLiberation Army from March2012to June2012, in terms of22factors such as gestationalage and birth weight, and then to proceed statistically.Results1、In this study, a total of40cases suffered primary respiratory suspension among the103cases of AOP children, the incident rate was38.8%, and secondary apnea63cases, theincident rate was61.2%. In the early phase of AOP, apnea is of a higher incidence,45.6%incident rate within12hours;35%incident rate between12hours to two days;12cases(11.7%) between2days to5days, primary respiratory suspension within five days, andsecondary apnea can be throughout the course of the disease.2、Smaller birth weight and gestational age can result in higher incident rate of apne,and primary apnea.the incidence of secondary apnea is slightly lower than primary apnea.28cases of infection diseases, apnea incidence27.2%; preterm children with centralnervous system diseases, a total of41cases, incidence39.8%;21cases of neonatalrespiratory distress syndrome, the rate is13.1%. Metabolic disorders50cases, accountingfor48.5%. 3、After conducting analysis on the103cases of AOP and non-AOP, and statisticalanalysis on22factors: The8types of high-risk factors are: gestational age less than32weeks, birth weight <1500g, neonatal pneumonia, acidosis, respiratory distress syndrome,intracranial hemorrhage, anemia hypoxic-ischemic encephalopathy, meconium aspirationsyndrome, and hypocalcemia.The result of P <0.05by the case group and control grouphas statistical significance.4、Result of single-factor logistic regression analysis of the high-risk factors isgestational age less than32weeks, birth weight <1500g, and acidosis are high-risk factorsfor AOP. P values (0.039,0.000,0.000) are less than0.05are considered statisticallysignificant.Conclusion1、Apnea relates to birth weight and gestational age: the smaller the birth weight andgestational age, the higher incident rate of apnea; The smaller the gestational age and birthweight, the higher incidence of primary apnea. Secondary apneas incident rate is slightlylower than the primary apnea.2、Apnea relates to postnatal time: apnea incident rate is much higher during the earlyphase, primary apnea within five days, and secondary apnea can occur throughout theentire phase of disease.3、Ggestational age less than32weeks, birth weight <1500g, and acidosis arehigh-risk incident factors of AOP of preterm children. Children with these factors shouldbe should be cautiously and intensively cared, nursed and improve prognosis.