The Research Of Kidney Disease Animal Methods On The Clinic Treatment Combine Traditional Chinese And Western Medicine

Kidney diseases are a kind of disease which have complex pathogenesis, the diagnosis of this disease was usually delayed and treatment difficult. By using animal model, can help us understanding the occurrence and development of diseases, searching for the best therapeutic program and screening effective medicines. At present, more and more kidney disease animal model were reported in the literature, but they were still a mixed bag. Some of them are in the early stages of production, cannot effectively simulate the human disease. How to choose the best model to guide the clinical treatment is a confused question. With the documentation method, the paper collected literatures about kidney disease animal model in recent years. Combined with western medicine of disease and syndrome in TCM, the models were classified systematize. The modeling methods, characters and clinical applications are summarized, and clarify its merit and shortcoming so that the researchers can choose the best model. At last, this study talks about the selection of experimental objects, the process of operation, the analyses of experimental result and the innovation of scientific research. Making an objective evaluation about how to guide the Chinese and western medicine in clinical treatment and the development tendency in the future. Through the systemically and comparatively summarizes, we may safely draw the conclusion that although there are various building methods, the animals are different from human, in the building method and model evaluation index still has some limitations, this still needs further study. Researchers should choose different animal models in base of the investigation of primary disease in order to help them discuss the relationship among renal pathology, biochemical criterion and clinical manifestation, expound pathogenesis of kidney diseases and make a screen of effective drugs. Only by this way, kidney disease animal models can pay an important role in the development of nephrology and even medical career..