Prepatation And Evaluation Of Guanqin Kegan Pills

Subject:To preparate and evaluate the Chinese medicine named Guanqin Kegan Pillsused to treat influenza，and then，study on its preparation process，quality standard，Preliminary stability and pharmacodynamics investigation research.Methods:Study on theextraction、concentration、drying and molding process by single factor experiment andorthogonal experiment，and have anointed rate，sulfide content，Hyperin content，Baicalincontent for important indexes， to determine the preparation process. With thin layerchromatoGraphy (TLC) each other to medicine by TLC， by HPLC root of herbaceousHyperin， Baicalin of on the content determination， formulating qualitystandards.Investigate the stability of the preparation at room temperature.Study on thepharmacodynamics of the Guanqin Kegan Pills with the phlegm stasis animalmodels.Results:The optimal preparation process is out.Thin layer chromatography (TLC)can be helpful to the Trichosanthes kirilowii Maxim，Allium macrostemon Bgecortexeffectively identify.Preparations for the content of Hyperin2.1mg/pill limit，Baicalin117μg/pill limit.Preliminary stability test results show that the preparation roomtemperature conditions stable quality. Pharmacodynamics experiment shows that the agentsfor influenza has good curative effect. Conclusion:Guanqin Kegan Pills the idealmedicine compound preparations， safe and effective， quality control， and stable.