The Features Of Pressure Distribution Of Rest Urethral Pressure Profile In Female Urethra

Objective: to investigate the features of pressure distribution of rest urethral pressureprofile in the female urethra.Methods: Totally55adult females referred for urodynamic evaluation of lowerurinary tract symptoms were included in this study, mean age(41±11) yrs. Resturethral pressure profile (RUPP) were recorded in four different positions in theurethra (anterior/12o’clock, posterior/6o’clock, left/3o’clock and right/9o’clock).Randomized block design ANOVA was used to compare the data of the RUPP indifferent catheter orientations with SPSS software (16.0).Results: The maximum urethral closure pressure (MUCP) is always highest in theanterior position （P<0.01)and lowest in the posterior position（P<0.001), and nodifference was noted between the left and right positions（P=0.571). The functionalurethral length shows longest in the posterior position（P<0.01) and shortest in theanterior position（P<0.01), and no difference was noted between left and rightpositions（P=0.717). The majority of RUPP curves are parabolic curves, highpressure zone and highest MUCP locating on the middle or mid-distal junction part ofthe urethra.Conclusions: The present study demonstrated that RUPP having significantanisotropic variations at the anterior and posterior positions and showing symmetriccharacteristic at the lateral positions. The features of the pressure distribution of theRUPP correspond to the anatomical and physiological features of the female urethra.