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Clinical Curative Effect Observation Of Slow-release Local Chemotherapy With Doxorubicin Hydrochloride In The Glioma

Posted on:2014-01-25Degree:MasterType:Thesis
Country:ChinaCandidate:L R FangFull Text:PDF
GTID:2254330401989772Subject:Surgery
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Objective: Glioma ordinary operation cure rate low, the prognosis effect is notgood. Therefore, discuss the effect of slow-release local chemotherapy withDoxorubicin hydrochloride in the glioma new operation. Methods: For datacollection and follow-up survey of77cases of complete medical record.According to the operation treatment is divided into Group A:Simple surgerygroup(26cases)、Group B:Postoperative only a general put, chemotherapy group(24cases)、Group C:Implant chemotherapy pump local chemotherapy group(27cases), to compare the survival time and survival rate.Results: ABC threegroups the median surial were18.7months and25.2months and31.8months,drawing the survival curves, the Log-rank test differences between the threegroups (χ~2=15.014, P<0.05),the survival rate of the slow-release localchemotherapy with Doxorubicin hydrochloride in the glioma operation is thehighest in the three operation methods. The three groups are different(P<0.05).In statistics,the three groups do not exit different in1or2years(P>0.05), Onlythree years of survival rate is differently(P<0.05).Conclusions: In the clinical,slow-release local chemotherapy with Doxorubicin hydrochloride in the gliomaoperation can improve Postoperative patients survival, the prognosis effect isgood, so it can try to use in the clinical...
Keywords/Search Tags:the slow-release local chemotherapy, Doxorubicin hydrochloride, glioma, surial
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