Analysis Of Prognosis Related Factors Of Post Cardiac Arrest Syndrome Patients

Objective To analysis Post-Cardiac arrest syndrome patients，eventually dieprognosis and neurological recovery prognosis and prognostic factors beforeand after the recovery, to explore independent risk factors of patients with earlycardiovascular failure after successful cardiopulmonary resuscitation to providethe prognosis assessing basis for clinical workers.Methods53successful cardiopulmonary resuscitation cases (survival≥24h)from December2010to July2012were selected in EICU ward of the FirstAffiliated Hospital of Anhui Medical University, which were divided, according tothe ultimately survival outcomes, into A group (survival within48hours), Bgroup (survival48hours after death), C group (discharged alive)； according toCPC scores,into good neurological outcome group of CPC score1to2points,bad neurological outcome group of CPC score3to4points, the death group；according to the appearance of early cardiovascular failure, into the earlycardiovascular failure group and the non-cardiovascular failure group.Collecting history and detecting and recording the related indicators afteradmission, using appropriate statistical methods to analysis relevant clinicaldatas.Results1.A group, B group, C group comparison: the factors before recovery:gender, age, location of recovery, recovery executor, the onset disease were notstatistically different (P>0.05), the relevant factors with patients，ultimatelysurvival outcome: the initial rhythm, CPR start time, CPR duration, and the basisof a history of cardiovascular disease (P <0.05or P <0.01)；the factors after recovery: within24hours whether SIRS、blood sugar disorders、cardiovascularfailure and multiple organ dysfunction after cardiopulmonary resuscitation wereall associated with patients，survival prognosis(P <0.05or P <0.01), SOFAscores and the APACHII scores were correlated factors.12-24h blood lactatevalues in group A patients was significantly higher than that in group B andgroup C (P <0.01), significantly higher in the death group (group A and B)patients of12-24h blood PCT values after recovery than group C,the differencebetween the groups was statistically significant (P <0.01),CRP values showedno differences between the three groups. Rescue too late、 long duration toCPR、 the initial rhythm of non-defibrillator cardiac rhythm and elderlyresuscitation were all related to cardiovascular failure (P <0.05or P <0.01).2.Neurological outcomes related factors: CPR start time, CPR whether SIRS、cardiovascular failure after cardiopulmonary resuscitation and duration, within24hours24hours SOFA scores、APACHIIscores、GCS scores were all associatedwith patients，neurological recovery prognosis(P <0.05or P <0.01).Conclusion Cardiac arrest syndrome is a complex disease, its prognosis isinfluenced by multiple factors. The underlying diseases, initial rhythm, the time ofstarting CPR and restoration of spontaneous circulation，as same as whetherthere is a disorder of acid-base balance and blood sugar, whether SIRS, MODSand early cardiovascular failure after cardiopulmonary resuscitation were allsignificantly correlated with the outcome. In addition, APACHII scores, SOFAscores can predict the prognosis of patients and neurological recovery,According to the various affecting factors, to reduce mortality and improve nervefunction prognosis still need clinical workers unremitting efforts.