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DWI For Cervical Lymphoma And Squamous Cell Carcinoma Of The Cervical Lymph Node Metastasis Preliminary Study Of The Differential

Posted on:2014-09-01Degree:MasterType:Thesis
Country:ChinaCandidate:K ZhangFull Text:PDF
GTID:2254330398961688Subject:Imaging and nuclear medicine
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Backgrounds and Objective diffusion weighted magnetic resonance imaging (diffusion-weighted imaging, DWI) is a recent MRI of a new technology, is currently the only for observing the water molecules in vivo diffusion motion of imaging method, The macro performance with apparent diffusion coefficient (apparent diffusion coefficient, ADC) said. Has now become in the cerebral ischemia and cerebral infarction in super acute stage of diagnosis of regular sequence. Tumor lesions close-grained degree, histological type, cell differentiation degree and the tumor pathological classification with ADC values have high correlation, Made according to the ADC value in qualitative diagnosis and differential diagnosis possible.This study discusses the ADC values under the neck lymphoma and squamous carcinoma metastases to the lymph nodes between the differential value, at the different b values,calculate the area under the ROC curve, selecting the best ADC values for both the differential with high sensitivity and specificity.Materials and methods Collect my hospital in October of2012to February of2012first diagnosis of cervical lymphoma and squamous carcinoma patients with lymph node metastases, male35cases,16cases of women, age4-79, the average age of50. Lymphoma27cases, including20cases of non-hodgkin’s lymphoma,7cases of hodgkin’s lymphoma;24cases of head and neck squamous carcinoma of lymph node metastases. Were confirmed by lymph node biopsy or postoperative pathology.Use produced by philips company philips Achieva more than3.0T TX source emission, magnetic resonance Imaging system using SENSE-NV-16channel head and neck joint coil, in addition to the conventional scanning head and neck, DWI scan using Single excitation can spin Echo Planar Echo Imaging (Single shot-Echo Planar Imaging SE-EPI) technology, the scanning layer thickness, layer spacing with axial T1WI and T2WI scope in the same way, so that can accurately locating of cervical lymph nodes. In axis X, Y and Z three directions on sensitive gradient pulses, respectively take0、600s/mm2、800s/mm2and1000s/mm2was four groups b value, get different b values under the DWI and ADC images can lymph node lesions, were measured under different b values lymph node lesions of ADC values.The measurement data with the (x±S), between the groups was compared using two sample t test, P<0.05considered statistically significant difference.Result The b value of600s/mm2, lymphoma and metastasis tumor ADC values were0.75±0.14×10-3mm2/s and1.12±0.12×10-3mm2/s, the b value of800s/mm2, lymphoma and metastasis tumor ADC values were0.68±0.11×10-3mm2/s and1.02±0.12×10-3mm2/s, the b value of1000s/mm2, lymphoma and metastases tumor ADC values were0.64±0.10×10-3mm2/s and0.96±0.13×10-3mm2/s, Under the different b values, cervical lymphoma and squamous carcinoma of cervical lymph node metastases of ADC values between difference had statistical significance (P<0.05). Under different b values, lymphoma and metastasis tumor in value take800s/mm2and1000s/mm2no statistically significant difference between them (P>0.05), there was statistically significant difference between the other groups (P<0.05). under different b values, lymphoma and squamous carcinoma of cervical lymph node metastases of ADC values are can be identified for both, and in the b value is1000s/mm2area under the curve of maximum, diagnostic value of maximum, when the ADC diagnosis of optimal threshold value is0.741×10-3mm2/s.Conclusion For cervical lymphoma and squamous carcinoma of cervical lymph node metastases can be identified by ADC values can determine...
Keywords/Search Tags:diffusion weighted imaging, cervical, lymphoma, squamous cellcarcinoma, lymph node metastasis, identification
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