Evaluation Of Carotid Artery Wall Movement In Diabetes With Velocity Vector Imaging-a Preliminary Study

Objective：The study was performed on normal people carotid artery,diabeteswith carotid artery plaque and diabetes without carotid artery plaque usingvelocity vector imaging(VVI)at test state．The axial and longitudinal wallmovement characteristics in same artery segment of the3groups were comparedand quantitative analyzed．Thus the value of VVI technology in carotid arterymechanics research was evaluated．Method:60patients with diabetes who wereexamined in our ultrasound department from September2011to June2012wereinvolved．The patients were divided into group A(30cases)and group B(30cases)according the vascular complications(including Macroangiopathy andMicroangiopathy)．Patients without vascular complications belong to groupA,others belong to group B．These patients，30healthy volunteers who were fromout．patient clinic in the corresponding period were supplied as normal controlgroup．General conditions of the patients with diabetes and the healthy subjectsincluding age，sex，BP，HR,BMI were recorded,and biochemical indicator such asTG,TC，LDL were included too．Velocity Vector imaging(VVI) was performed withSiemens Acuson S2000ultrasonic diagnostic equipment.The reference point wasput in the center of lumina.Time to the peak of velocity(VTTP)，maximum ofvelocity(Vmax)，maximum of strain(Smax)，and maximum of strain rate(SRmax)ofsix segent(anterolateral wall，anterior wall,anteromedial wall,posteromedialwall,posterior wall，posterolateral wall)were measured，which were supplied byVVI automatic analysis software.General average of each index in3continualheart beating cycles was recorded.Results:Age，Sex，BP，HR,BMI had no significant differences in group A，B and control group(P>0．05)．IMT of carotid had nosignificant difference between control group and group A，group A and groupB(P>O.05)respectively，but there was significant difference between controlgroup and group B(P<O．05)．TG．TC and LDL in group A and B were higher thanthose in control group(P<0．05)，and there were no significant differencesbetween group A and group B(P>O．05)．There were significant differences in somesegments in control group，group A and group B，Vmax of anterior wall，anterolateral wall and posterolateral wall were higher than those of posteriorwall，posteromedial wall and anteromedial wall(P<0．05)．VTTP,Vmax，Smax andSRmax of corresponding segments had significant differences in group A，groupB and control group(P<0.05)，control group>group A>group B(P<0.05)．Conclusion：The velocity vector imaging can be applied to assess the biomechanical changesof the carotid artery wall in patients with diabetes．VVI is of value inmonitoring the early diabetic vascular change and the evolution ofcomplications．For the early pathological changes of diabetes arteriosclerosis,also caused no obvious morphological change of blood vessel walls, conventionalultrasound cannot distinguish differences and normal blood vessels.Velocityvector imaging technology as a new kind of detection of arterial elastic functioncheck method, real-time, noninvasive, convenient operation and goodrepeatability.