Study Of Prevalence And Relative Factors To The Children’ Autism In Ningxia

Objective:(1)Using the capture-recapture method to calculate theautism`s prevalence in children aged from0to14.(2)To study theinfluence factors of autism: including the mothers’ living environment,medication history and emotions in6month before their pregnancy andin the first6months of pregnancy; maternal complications, pregnancyhistory; the environment of the father in the6months prior to themother’s pregnancy; disease history of children; the parenting of childrenwith autism.Methods:(1)Apply capture-recapture principles to design datacollection approach: To collect all the children with autism under14-year-old(including14) diagnosed during the phase of2011-10-1to2012-10-1.The first channel，The First People’s Hospital of Yinchuan,Ningxia People’s Hospital, Affiliated Hospital of Ningxia MedicalUniversity. The second channel, Disabled Persons’ Federation of Ningxia（including its subordinates），Maternal and Child Health Hospital, twoAutism Rehabilitation schools in Ningxia---Family Xingyu and AiXinyuan. To calculate the prevalence of autism aged0-14after excludedthe overlaps.(2)42children with autism had been investigated to study theinfluence factors of etiology on autism, including information of familyhistory; the mothers’ living environment, medication history and emotions in6month before their pregnancy and in the first6months ofpregnancy; maternal complications and neonatal complications;pregnancy history; the environmental conditions of the father beforemother’s pregnancy; child rearing. To study the impact of parents onautism`s prevalence by following statistical methods: using the chi-squaretest to compare the enumeration data of two groups. using t-test andnon-conditional logistic regression for measurement data`s multivariateanalysis.Results:(1) The total number of autisms from0to14years old inNingxia was698,and its prevalence was5.178/10000, after nvestigatingall the autism diagnosed during the phase of2012-10-1.(2)These factors related to autism are statistically significant: halfa year before pregnancy, mothers’exposure to lonizing radiation [6.708(1.825-24.658)], exposure to toxic chemicals[3.747(1.279-10.981)],higher tension at work [2.418(1.180-4.955)];mostly staying in bad moodduring early6months of pregnancy[2.397(1.128-5.091)]; the age ofmothers during pregnancy[1.571(1.030-2.396)];6months prior toconception, fathers’high intensity of physicalwork[0.435(0.227-0.836)]and fathers’exposure to lonizing radiation[2.760(1.150-6.625)];the gestational age[0.780(0.611-0.998)]and birthweight [0.385(0.147-1.006)]; the parenting[0.494(0.353-0.692)] andrelationships in family [0.423(0.215-0.830)]during children’s growingup.Conclusion:(1) Using the capture-recapture method, the number ofautism under14-year-old in Ningxia was449to937and its prevalencewas3.333/10000to6.951/10000lower than the result of investigation of the same age group in China.(2) Current study found that some diseases and factors in the periodof mother pregnancy, perinatal, infant and early childhood might be theinfluencing factors of autism occurring, especially exposure to ionizingradiation and toxic chemicals, emotions, age of the mother duringpregnancy, the work of the father before the mother’s pregnancy,gestational age and birth weight, which are supposed to arouse ourattention. And it is probably effective in preventing and reducing theoccurrence of autism in children if we could control exposure to thesefactors. During the upbringing of children with autism, we can see morespoil or abuse, poorer family relationships, so the parents of autism needfurther improvement on parenting.