Heartache The Clinical Curative Effect Of Treatment Of Unstable Angina And Its Influence On Serum Levels Of Mmp - 2

Purpose:Observe Soothing Liver reducing phlegm and removing blood stasis (Xintongfang decoction)and treat unstable angina pectoris (UAP) clinical curative effect and impact on serum matrix metalloproteinase 2 (MMP-2)of the card patient of phlegm and blood stasis qi stagnation and obstruction of heart meridian,probes into the intervention mechanism of its therapeutical unstable angina pectoris.Method:Adopt single blind law at random,is it observe standard patient is it treat 30 of group (Xintongfang decoction+Western medicine foundation treat) and contrast 30 of group to divide into at random to accord with (Western medicine foundation will be treated), use medicine one week in succession,carry on clinical curative effect observe and measure two group horizontal change of MMP-2 in front and at the back of treating.Result:(1)The clinical card of two groups of patients’Chinese medicine is waited and improved notably, and treat a group of Chinese medicine cards and is waited and always superior to contrasting the group efficiently;(2)Two groups of angina pectoris breaks out in number of times and duration and improves, and it is superior to contrasting the group treating the group;(3)Two groups of ECG are improved, two groups do not relatively have obvious difference.(4)Treating group phlegm and blood stasis qi stagnation and obstruction of heart meridian stops the reducing rate and is obviously higher than contrasting the group;(5)MMP-2 density presents the downward trend in the plasma after two groups treat, compared with the situation before treating there is a remarkable difference; (6)After treating for 4 weeks, it is greater than contrasting the group treating the fall of group MMP-2;(7)Follow up a case by regular visits to and find that Xintongfang decoction treats group’s acute cardiovascular incident incidence and is less than contrasting the group.Conclusion:1.Xintongfang decoction has good curative effect to treat UAP, can obviously improve the clinical symptom of Chinese medicine and ECG,alleviate angina pectoris, reduced acute cardiovascular incident incidence again recently, UAP had certain clinical meanings to treating.2.MMP-2 level that Xintongfang decoction can reduce a UAP patient in the plasma,slow down the progress of atheromatous plaque, stabilizes atheromatous plaque. This may treat one of the effective mechanisms of UAP for Soothing Liver reducing phlegm and removing blood stasis (Xintongfang decoction).