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Based On The Lobule On The Top Of The Segmentation Of Brain Connections

Posted on:2013-12-06Degree:MasterType:Thesis
Country:ChinaCandidate:W Q WanFull Text:PDF
GTID:2244330374986154Subject:Biomedical engineering
Abstract/Summary:PDF Full Text Request
The superior parietal lobule (SPL) is a functionally and anatomically heterogeneousregion and has been parcellated into different kinds of subregions using cyto-ormyeloarchitectonic methods. However, these parcellation schemes cannot be directlyapplied to the living human brain and always with inconsistent subdivisions. In thepresent study, we aimed to parcellate the SPL in vivo using diffusion MRI (dMRI) andto establish a method to extract the SPL subregions in the living human brain. UsingdMRI, three subregions were identified in the human SPL with differential anatomicalconnectivity profiles. Then the SPL subregional probability maps, together with thepatterns of the anatomical and resting-state functional connectivities were acquired andsystematically revealed. Moreover, different connectivity fingerprints of the threesubregions were also characterized. To our knowledge, this is the first study toinvestigate the subdivision of human SPL using non-invasive diffusion tensor imaging(DTI) technique, which will facilitate the future study of this region.
Keywords/Search Tags:superior parietal lobule, tractography, diffusion MRI, resting-state, parcellation
PDF Full Text Request
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