74 Cases Of Patients With Diabetic Foot Infection Pathogen Characteristics And Drug Susceptibility Were Retrospectively Analyzed

Objective:Diabetes foot ulcer with serious disability which bring the body and psychological burden, and the infection is the primary factors caused amputation. The poor blood glucose control and immune function defects of diabetes patients cause people to drop resistance, more likely to lead to foot infection, and further aggravating illness development, to effectively control the infection can obviously improve the prognosis, reducing amputation rate and mortality rate. This study through the dongzhimen hospital during2007and2012,74cases of patients with diabetes foot ulcer wound bacteria cultures and secretion of drug sensitive test retrospectie analysis, this paper discusses the common bacterium group and related medicine sensitivity of the diabetic foot infection wound. Thus it can be useful to choos sensitive antibiotics for clinical treatment of diabetic foot ulcers infection, and to enhance clinical curative effect, reduce the amputation and patients with the risk of death.Methods:After screening, I chose74patients of diabetes foot Wanger classification level1～5patients into standard from Beijing dongzhimen hospital in September2007to February2012. Using the information acquisition were related to and analysis the related data, in order to understand the dongzhimen hospital infection in patients with diabetes foot microorganism cultivation of drug sensitive bacteria and related, summarize the relevant conclusions, guiding the clinical experience antibiotic use, improve the clinical treatment effect.Results:The statistical analysis results of the data collected, microorganism culture results show that in74patients with infective diabetes foot patients, there were54male patients, accounting for72.97%, female patients with20cases, accounting for24.03%of the total number of patients.74patients with an average age of67.31±9.71699years, and the diabetes course with an average age of14.5±7.44747years, from7days to30years differ, but in more than10years. Diabetes foot course in1day to4years already, include acute infections and long-term chronic infection patients. Diabetes foot Wagner from grade1to grade level4dollars. Among them, the grade1patients in1,1.35%of the total number, level2patients25cases,33.78%, grade3patients in14cases, accounting for18.91%of the total, the level4patients in33patients, with44.59%of the total.74patients were training out of142cases of bacterium group, including single bacterium group of59people, accounting for79.73%of the total number of patients. Composite flora of15people, accounting for20.27%, composite flora double strains of bacteria infections in14, reason flora infection1person. In142strains of bacteria, there were38strains of gram positive coccus, accounting for26.76%of the total number, including dung bowel aureus (group D)15strains, staphylococcus aureus and strains, solidify enzyme negative staphylococcus6(staphylococcus epidermidis, staphylococcus aureus (MRSA) the two strains, coriolis staphylococcus aureus, imitate, staphylococci haemolyticus1and excrement bowel aureus (group D) each1strain. Gram negative bacteria totaling102strains of bacteria accounted for71.83%, among them escherichia coli25strains, pseudomonas aeruginosa20strains, pneumonia clay "twelve strains bacteria, drain enterbacteriaceae10strains of each, MaShi Morgan eight strains bacteria, proteus mirabilis6(acetic acid calcium bowman composite acinetobacter3plants, producing gas enterbacteriaceae and put the two strains bacteria’s citric acid, citric acid compound, Florida’s bacteria produce acid clay" bacteria, method surname citric acid bacillus, gram citric acid bacillus, xylose oxidation production base, common bacteria xylose oxidation subspecies deformation bacteria, eosinophilic malt that keep form afterbirth fungus, calcium carbonate bowman composite acinetobacter, thank the bird acid clay "bacteria, fluorescence pseudomonas goo, Mr Charest bacteria, middle enterbacteriaceae1accounted for the plant. And develop two strains white candida, accounting for1.4%of the total number of bacterial flora.Results show that the drug susceptibility, gram positive coccus to vancomycin, nitrofurantoin, With colin, rifabutin more sensitive, did not appear to vancomycin resistance, of penicillin kind, big ring lactone class and quinolone antibacterial all appear different levels of drug resistance. Gram negative bacteria to penicillin and generation, the second generation cephalosporins and three generation cephalosporin present different degree of resistance, the fourth generation cephalosporin despite a certain drug resistance, but still relatively more sensitive. To aminoglycoside michiyo card star and quinolone antibacterial levofloxacin also were very sensitive to the mold, like propylene carbon imipenem, beauty e.faecalis and compound preparation cefoperazone/suibactam was, piperacillin he sulbactam was sodium were sensitive antibiotics, resistance is relatively low.Conclusion:In recent years,The widespread use of antibiotic causes diabetes foot ulcer patients infected pathogen spectrum constant change, existing gram-positive bacterial infection growing trend, and resistant strains and quantity extent also showed a rising trend. Continuing to diabetes foot infection of the pathogen and its drug resistance monitoring, can provide clinical anti-infection treatment for the basis, improve the curative effect of empirical fight infection.